{"id":"W4223528634","doi":"10.1002/cmdc.202200161","title":"Identification of 4‐Anilinoquin(az)oline as a Cell‐Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype**","year":2022,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; University of North Carolina at Chapel Hill; National Institutes of Health; Canada Foundation for Innovation; Innovative Medicines Initiative; Wellcome Trust","keywords":"Chemotype; Kinase; Chemistry; Protein kinase inhibitor; Identification (biology); Protein kinase A; Biochemistry; Cancer research; Biology; Computational biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":{"n_in":0,"stratum":"fund_new","weight":1678.9,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Medicinal chemistry identification of a PKN3 kinase inhibitor chemotype."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"The work identifies a protein kinase inhibitor for cancer research, not a study of research."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Medicinal chemistry identification of a PKN3 inhibitor chemotype; domain drug discovery."}}}