{"id":"W4223550633","doi":"10.1016/j.jaad.2022.04.006","title":"Associations of combined lifestyle and genetic risks with incident psoriasis: A prospective cohort study among UK Biobank participants of European ancestry","year":2022,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; Medical Research Council; National Natural Science Foundation of China","keywords":"Medicine; Biobank; Hazard ratio; Psoriasis; Cohort study; Confidence interval; Population; Risk assessment; Prospective cohort study; Body mass index; Relative risk; Cohort; Lower risk; Demography; Internal medicine; Environmental health; Bioinformatics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003863596,0.0001454809,0.0008527727,0.0001565296,0.0001547481,0.000002530785,0.0003795201,0.00004748506,0.00002071879],"category_scores_gemma":[0.0001027449,0.0001008392,0.0001199673,0.0003498056,0.0007316982,0.00004231925,0.0001940269,0.0003664093,8.54007e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004525077,"about_ca_system_score_gemma":0.00009463408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001593022,"about_ca_topic_score_gemma":0.00001771241,"domain_scores_codex":[0.9971451,0.001559165,0.0007904853,0.0001554097,0.0001330828,0.0002167531],"domain_scores_gemma":[0.9963226,0.0002284114,0.003185483,0.000144787,0.00008791711,0.0000307415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005462752,0.0005772065,0.9887715,0.000007656051,0.001902549,0.00002215587,0.001166923,0.00006559159,0.00644451,0.00001695402,0.0001310225,0.0003476618],"study_design_scores_gemma":[0.002404525,0.001202098,0.9826162,0.00002068416,0.001052424,0.000575175,0.001859848,0.000001849346,0.01011642,0.00004745007,0.00001760783,0.00008569439],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981295,0.0009542023,0.000004415732,0.0002925264,0.0001309281,0.0003689499,0.00006532497,0.000005010678,0.00004907343],"genre_scores_gemma":[0.999679,0.0001332968,0.00007575172,0.00004776062,0.00001332707,0.00001878142,0.000001946405,0.0000129955,0.0000171204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006155267,"threshold_uncertainty_score":0.4112102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0315458950562501,"score_gpt":0.2973487181065467,"score_spread":0.2658028230502966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}