{"id":"W4223573620","doi":"10.1093/biolre/ioac070","title":"Activin A promotes hyaluronan production and upregulates versican expression in human granulosa cells","year":2022,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Versican; Cell biology; Biology; Chromatin immunoprecipitation; Signal transduction; Endocrinology; Internal medicine; Extracellular matrix; Gene expression; Biochemistry; Proteoglycan; Promoter; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003303961,0.0001077375,0.0001294015,0.00009560141,0.0001590862,0.000003589264,0.00009840883,0.0000676581,0.00002006711],"category_scores_gemma":[0.0001243398,0.0001125094,0.00003513191,0.00009968974,0.0001776538,0.000006518625,0.0001623203,0.00009133991,3.543408e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000206824,"about_ca_system_score_gemma":0.00003330282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002772422,"about_ca_topic_score_gemma":0.0000101942,"domain_scores_codex":[0.9987589,0.0001987832,0.0001862293,0.0006441494,0.00007290181,0.0001391117],"domain_scores_gemma":[0.9994149,0.000006285545,0.000143522,0.0003739126,0.0000352044,0.0000261911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443342,0.0001794518,0.01171419,0.00002671948,0.00001346523,4.211795e-7,0.0001521,0.0001736996,0.9819871,0.000008488214,0.0002207918,0.005379205],"study_design_scores_gemma":[0.0002094053,0.0005973674,0.01119203,0.00001287042,0.000008505325,0.00001260585,0.0001733052,0.000004730011,0.9823173,0.000166888,0.005189382,0.0001155769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973738,0.001890919,0.0000200608,0.0001140619,0.0002861038,0.0002661969,0.00001015984,0.00001797433,0.00002076317],"genre_scores_gemma":[0.9990287,0.00002558625,0.0003571573,0.00000457445,0.000187443,0.00005887954,0.0001248219,0.00001276942,0.0002000224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005263628,"threshold_uncertainty_score":0.4588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009075262273245451,"score_gpt":0.2445687600452211,"score_spread":0.2354934977719756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}