{"id":"W4223573620","doi":"10.1093/biolre/ioac070","title":"Activin A promotes hyaluronan production and upregulates versican expression in human granulosa cells","year":2022,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Versican; Cell biology; Biology; Chromatin immunoprecipitation; Signal transduction; Endocrinology; Internal medicine; Extracellular matrix; Gene expression; Biochemistry; Proteoglycan; Promoter; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941984,0.0002429955,0.0002558342,0.0003050434,0.0001831583,0.0003390396,0.0000671213,0.0001611536,0.001389089],"category_scores_gemma":[0.0001205819,0.0001217476,0.0002971287,0.0002233309,0.0002150179,0.0001084675,0.0002085712,0.0003320283,0.0004191915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000265693,"about_ca_system_score_gemma":0.0002365944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001540749,"about_ca_topic_score_gemma":0.001454975,"domain_scores_codex":[0.999886,0.00002032816,0.00001445895,0.00002146834,0.00002419756,0.00003350565],"domain_scores_gemma":[0.9999219,0.00002451479,0.0000119072,0.00001217231,0.000008651187,0.0000207924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002534229,0.00005649482,0.0003915576,0.00006416323,0.000008535114,0.0001335688,0.00008422595,0.00006828772,0.996511,0.0000766036,0.0001209883,0.002231055],"study_design_scores_gemma":[0.00008307616,0.0005532939,0.01560267,0.00001753847,0.00004430103,0.0002933733,0.0001429027,0.001354284,0.9725139,0.00008965763,0.009296036,0.000009036112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902653,0.004218068,0.001716273,0.0001895863,0.0000570617,0.00007243718,0.0004660517,0.0000772783,0.002938053],"genre_scores_gemma":[0.9920963,0.001855771,0.001407444,0.0001215198,0.00003271286,0.00005056096,0.0007734986,0.00001200271,0.003650111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540749,"threshold_uncertainty_score":0.004646957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009075262273245451,"score_gpt":0.2445687600452211,"score_spread":0.2354934977719756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}