{"id":"W4223575134","doi":"10.21203/rs.3.rs-1536905/v1","title":"WITHDRAWN: Reduced tumor volume and increased necrosis of human breast tumor xenograft in mice pretreated by a cocktail of three specific anti-HER2 scFvs: Involvement of stereological methods","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Phage display; Molecular biology; Antibody; Breast tumor; Chemistry; Breast cancer; Immunology; Cancer; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001575804,0.000578979,0.0004128461,0.0005335807,0.0001528088,0.0002456682,0.0003584085,0.0005495237,0.009688636],"category_scores_gemma":[0.0001404794,0.0001695082,0.000403036,0.0003063386,0.0003482684,0.0002567539,0.0001419934,0.001262465,0.0011295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003064773,"about_ca_system_score_gemma":0.0004158886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002201774,"about_ca_topic_score_gemma":0.001180256,"domain_scores_codex":[0.9997633,0.00001954523,0.00001829672,0.00004996563,0.00007575291,0.00007304677],"domain_scores_gemma":[0.9998431,0.00003566556,0.00003397476,0.0000146644,0.00002040651,0.00005211646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001756251,0.0001763442,0.000209085,0.0001001204,0.00002844944,0.0001486069,0.00002044309,0.0001786364,0.9917802,0.0003356632,0.00139575,0.003870312],"study_design_scores_gemma":[0.00007856039,0.0003673132,0.003611968,0.000004809695,0.00002855068,0.0002885945,0.00002466126,0.0006720069,0.9923866,0.00007469403,0.002456452,0.000005777593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9551109,0.0039297,0.01180361,0.001732751,0.001370816,0.000159122,0.01188216,0.001058747,0.01295215],"genre_scores_gemma":[0.9574373,0.001604383,0.006812693,0.0003835576,0.0001533056,0.0001829993,0.007303284,0.0001910368,0.02593144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009688636,"threshold_uncertainty_score":0.03241175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08599464658226451,"score_gpt":0.4160448649819106,"score_spread":0.3300502183996461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}