{"id":"W4223599799","doi":"10.1186/s13053-022-00220-6","title":"Germline BRCA1 and BRCA2 mutations and the risk of bladder or kidney cancer in Poland","year":2022,"lang":"en","type":"article","venue":"Hereditary Cancer in Clinical Practice","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; Women's College Hospital; University of Toronto","funders":"Pomorski Uniwersytet Medyczny W Szczecinie","keywords":"Medicine; Germline; Human genetics; Germline mutation; Bladder cancer; Kidney cancer; Oncology; Gynecology; Internal medicine; Cancer; Mutation; Cancer research; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003596399,0.0001936468,0.0003055697,0.0009447738,0.0002750716,0.0004380427,0.0002527772,0.0002845868,0.00114296],"category_scores_gemma":[0.0009405414,0.0002688307,0.0002351199,0.0007106148,0.000235431,0.000186537,0.0004470273,0.0002436699,0.0001147738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002258656,"about_ca_system_score_gemma":0.0003303306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005141874,"about_ca_topic_score_gemma":0.003511562,"domain_scores_codex":[0.999769,0.00004092086,0.00002827108,0.00007812001,0.00004444557,0.00003918901],"domain_scores_gemma":[0.9995641,0.00005874676,0.0002408592,0.00001966708,0.00003444541,0.00008226863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009821811,0.0000106071,0.9977579,0.00002027369,0.00003945149,0.0001765672,0.00006505549,0.00002586852,0.0004453677,0.00001508646,0.00003750973,0.001308247],"study_design_scores_gemma":[0.00001413476,0.00006580379,0.9982494,0.00001417891,0.0000410327,0.001076842,0.00009950718,0.00008519916,0.0001322404,0.00003570563,0.000183645,0.000002372492],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992967,0.000429715,0.00004078584,0.00002282632,0.00000151442,0.000002871234,0.00008194871,0.000001998173,0.0001215875],"genre_scores_gemma":[0.9994619,0.0002808433,0.00007481712,0.00001211668,0.000002976449,0.000002806245,0.00007576122,0.000001021842,0.00008772805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005141874,"threshold_uncertainty_score":0.01022393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02924976106179353,"score_gpt":0.3909781609123933,"score_spread":0.3617283998505998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}