{"id":"W4223599799","doi":"10.1186/s13053-022-00220-6","title":"Germline BRCA1 and BRCA2 mutations and the risk of bladder or kidney cancer in Poland","year":2022,"lang":"en","type":"article","venue":"Hereditary Cancer in Clinical Practice","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; Women's College Hospital; University of Toronto","funders":"Pomorski Uniwersytet Medyczny W Szczecinie","keywords":"Medicine; Germline; Human genetics; Germline mutation; Bladder cancer; Kidney cancer; Oncology; Gynecology; Internal medicine; Cancer; Mutation; Cancer research; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002013965,0.0001362225,0.000266773,0.00005520784,0.0001296124,0.00001495224,0.0001808964,0.00011309,0.0005414868],"category_scores_gemma":[0.00364124,0.000105633,0.00005774388,0.0002772593,0.0004484253,0.00002251531,0.0002753193,0.000606309,7.287209e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008413255,"about_ca_system_score_gemma":0.0009896457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00406736,"about_ca_topic_score_gemma":0.006561942,"domain_scores_codex":[0.9975838,0.0008756918,0.000685177,0.0004519082,0.0002133758,0.0001900368],"domain_scores_gemma":[0.9976471,0.001486591,0.0003597024,0.0003167502,0.0001033323,0.00008651109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02666347,0.001796336,0.6797442,0.0002873936,0.00248684,0.0002335075,0.004229293,0.03942321,0.002230764,0.0003932617,0.1023046,0.1402071],"study_design_scores_gemma":[0.02262073,0.001005574,0.5040953,0.0001006022,0.0008327355,0.0002511488,0.007232397,0.005269896,0.0004794619,0.001405007,0.4559523,0.000754817],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.944822,0.02840136,0.00006871947,0.0220916,0.001338984,0.0007366299,0.00137496,0.000008816334,0.001156917],"genre_scores_gemma":[0.9742667,0.01977895,0.0007924688,0.003835406,0.0005688624,0.0003934957,0.00003968906,0.00002603136,0.000298357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3536477,"threshold_uncertainty_score":0.6148659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02924976106179353,"score_gpt":0.3909781609123933,"score_spread":0.3617283998505998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}