{"id":"W4223618378","doi":"10.1016/j.isci.2022.104188","title":"Poly(I:C) enhances mesenchymal stem cell control of myeloid cells from COVID-19 patients","year":2022,"lang":"en","type":"article","venue":"iScience","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Ontario Institute for Regenerative Medicine; Ottawa Hospital","keywords":"Mesenchymal stem cell; Immune system; Priming (agriculture); Downregulation and upregulation; Effector; Transcriptome; Immunology; Cell biology; Myeloid; Biology; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008899783,0.0001689811,0.0003915332,0.0001914696,0.0003512683,0.00002545735,0.0006668812,0.00004789697,0.003034953],"category_scores_gemma":[0.000149609,0.0001450175,0.0001086929,0.0007942928,0.0003632589,0.0001194736,0.0003680489,0.000325371,0.0001036968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002836995,"about_ca_system_score_gemma":0.0008538917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008113558,"about_ca_topic_score_gemma":0.00001579811,"domain_scores_codex":[0.9960868,0.0002610116,0.000435958,0.0005893958,0.002085361,0.0005414993],"domain_scores_gemma":[0.9980285,0.0005173941,0.000224619,0.0005244887,0.0001463236,0.0005586816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005462348,0.0008316264,0.08103243,0.0001787717,0.00002694505,0.0001040223,0.002355908,0.0001440728,0.8959225,0.0000777888,0.004128152,0.01465151],"study_design_scores_gemma":[0.00682277,0.002711997,0.02867697,0.00004357163,0.00007440145,0.00001196221,0.003075723,0.003418187,0.9040881,0.0001765041,0.0504111,0.0004887407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852114,0.002081833,0.001659321,0.0006479113,0.0004984488,0.0007555461,0.0002453676,0.00004132416,0.008858837],"genre_scores_gemma":[0.9934183,0.00002545946,0.0002529487,0.0009542831,0.00005623156,0.00005601632,0.00001520559,0.00001504971,0.005206502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05235545,"threshold_uncertainty_score":0.9978764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02675041399606186,"score_gpt":0.2971077168932734,"score_spread":0.2703573028972115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}