{"id":"W4223620130","doi":"10.1007/s12079-022-00677-z","title":"Sustained AWT1 expression by Dupuytren’s disease myofibroblasts promotes a proinflammatory milieu","year":2022,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Dupuytren's Contracture and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Myofibroblast; Pathogenesis; Fibrosis; Cancer research; Downregulation and upregulation; Pathology; Biology; Medicine; Immunology; Inflammation; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003785518,0.0001313694,0.0002546819,0.0001313664,0.0003245352,0.00003556542,0.0001638208,0.00003129232,0.0001866273],"category_scores_gemma":[0.00003378811,0.0001035607,0.0001101956,0.0000877044,0.00003835821,0.0001593817,0.0001252483,0.0003628846,0.000001347846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008087406,"about_ca_system_score_gemma":0.0001360637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002979425,"about_ca_topic_score_gemma":4.602848e-7,"domain_scores_codex":[0.998738,0.0002325904,0.0004254646,0.0001097614,0.0003531339,0.000141057],"domain_scores_gemma":[0.9987463,0.0001394349,0.0004302416,0.0003093839,0.0001362687,0.0002383566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003886933,0.002261897,0.009615953,0.000381884,0.0002795281,0.0003528374,0.004756066,0.0001707056,0.962922,0.0001012859,0.006848866,0.008422097],"study_design_scores_gemma":[0.03886395,0.004876694,0.009585646,0.0025079,0.002671522,0.001004567,0.0134482,0.003304512,0.790898,0.00548054,0.1259792,0.001379271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835859,0.01348647,0.0001398555,0.001709389,0.00003932322,0.0003011106,0.00000713772,0.00002011783,0.0007106961],"genre_scores_gemma":[0.9971912,0.0003956541,0.001078799,0.0001996717,0.00003392545,0.00001668394,0.00004380345,0.00001858419,0.001021701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.172024,"threshold_uncertainty_score":0.4223083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007260144304811038,"score_gpt":0.2368462478020694,"score_spread":0.2295861034972584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}