{"id":"W4223632973","doi":"","title":"Plerixafor on a WHIM - Promise or Fantasy of a New CXCR4 Inhibitor for This Rare, but Important Syndrome?","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"CXCR4; Plerixafor; Hypogammaglobulinemia; Medicine; CXCR4 antagonist; Imiquimod; Rituximab; Immunology; Lymphoma; Antibody; Chemokine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051021,0.0002380012,0.0003790791,0.0002402502,0.0001865172,0.0005489193,0.0003086566,0.0007061243,0.003808071],"category_scores_gemma":[0.0005138463,0.00007240511,0.0003667785,0.0001719704,0.0004149062,0.001293151,0.0002512567,0.001447203,0.0008962303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00025178,"about_ca_system_score_gemma":0.000256078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002313138,"about_ca_topic_score_gemma":0.001413825,"domain_scores_codex":[0.9998543,0.00004455126,0.00001685391,0.00001718148,0.00003694972,0.00003011325],"domain_scores_gemma":[0.9998484,0.00006001684,0.00003209616,0.000006878297,0.00001862763,0.0000340965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003497617,0.0003451571,0.002719572,0.001896953,0.0002218343,0.005529141,0.0002534174,0.0005081374,0.02283037,0.01139664,0.06268783,0.8881133],"study_design_scores_gemma":[0.001745108,0.006031561,0.008532782,0.001532505,0.000330933,0.01844807,0.0005760004,0.000911481,0.008363446,0.00881923,0.9446218,0.0000871565],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.08027308,0.7821695,0.002595405,0.1071747,0.003993342,0.000119603,0.0004245568,0.0001932608,0.0230565],"genre_scores_gemma":[0.3049204,0.5334279,0.005032066,0.09809403,0.009965271,0.0001801227,0.001044445,0.0000975992,0.04723822],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.003808071,"threshold_uncertainty_score":0.0127393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03968636837099324,"score_gpt":0.2555448684175933,"score_spread":0.2158585000466001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}