{"id":"W4223900741","doi":"10.1089/ipm.09.02.03","title":"MRD: The Future Foundation of Solid Tumor Trials?","year":2022,"lang":"en","type":"article","venue":"Inside Precision Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CARE Canada","funders":"","keywords":"Medicine; Solid tumor; Internal medicine; Minimal residual disease; Family medicine; Clinical trial; Precision medicine; Disease; Oncology; Library science; Gerontology; Medical physics; Cancer; Pathology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05229284,0.001533497,0.005279446,0.001762164,0.001688968,0.009918655,0.003733455,0.01076258,0.03859145],"category_scores_gemma":[0.06285282,0.0007584698,0.002075484,0.001921788,0.01092699,0.02107846,0.005245247,0.01487146,0.01020736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006030214,"about_ca_system_score_gemma":0.01189397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002762369,"about_ca_topic_score_gemma":0.003113009,"domain_scores_codex":[0.9858947,0.008281418,0.00079251,0.001610793,0.002400648,0.001020033],"domain_scores_gemma":[0.9078847,0.06350355,0.004407535,0.00641169,0.009402105,0.008390403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002757214,0.0003263463,0.002115099,0.002149659,0.000237829,0.0003177027,0.0001912448,0.001951843,0.001316986,0.2156996,0.3209156,0.4520209],"study_design_scores_gemma":[0.000794602,0.0009266436,0.001546521,0.003922743,0.000234516,0.0004578421,0.0004609847,0.002351936,0.0006733197,0.3310752,0.6573881,0.0001676405],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00215781,0.2545647,0.01269358,0.7009169,0.01414984,0.00007620863,0.001026785,0.0004514952,0.01396273],"genre_scores_gemma":[0.1155104,0.3687417,0.03623822,0.3616261,0.09910183,0.0006429389,0.002446568,0.0006883083,0.01500396],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05229284,"threshold_uncertainty_score":0.2765543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426878292145473,"score_gpt":0.3201777943012603,"score_spread":0.2959090113798055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}