{"id":"W4223902686","doi":"10.1016/j.chemosphere.2022.134625","title":"Role of heavy metals (copper (Cu), arsenic (As), cadmium (Cd), iron (Fe) and lithium (Li)) induced neurotoxicity","year":2022,"lang":"en","type":"review","venue":"Chemosphere","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nutrasource","funders":"","keywords":"Neurodegeneration; Substantia nigra; Parkinson's disease; Neurotoxicity; Oxidative stress; Autophagy; Chemistry; Cadmium; Neuroscience; Cell biology; Internal medicine; Disease; Biochemistry; Medicine; Apoptosis; Biology; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002213291,0.0008007513,0.002772212,0.00006362928,0.0001358545,0.00003086157,0.000259816,0.0004761208,0.002464573],"category_scores_gemma":[0.0001451073,0.0006565647,0.0008367706,0.0004090005,0.00008025853,0.000083862,0.0003303595,0.0007754358,0.0001042907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002495478,"about_ca_system_score_gemma":0.0007492795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002272065,"about_ca_topic_score_gemma":0.00001477184,"domain_scores_codex":[0.9969169,0.0001951053,0.0007827037,0.001010401,0.0005834808,0.0005113689],"domain_scores_gemma":[0.9977235,0.0001135865,0.000567014,0.0009976326,0.00005902772,0.000539264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003021329,0.001900354,0.0001302801,0.03157244,0.00196769,0.0006313761,0.0001764382,3.507067e-7,0.002042511,0.0001450733,0.001417317,0.9597141],"study_design_scores_gemma":[0.001272095,0.0005386557,0.0001574146,0.002362709,0.004440547,0.000346108,0.0001027727,0.000007939571,0.002104733,0.000116971,0.9880523,0.0004977483],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03498871,0.9564305,6.107396e-7,0.00004153365,0.0002302523,0.002175093,0.0001894769,0.00009214012,0.005851697],"genre_scores_gemma":[0.0137423,0.9821743,0.0001489476,0.0002099526,0.0001517604,0.000518648,0.0003143184,0.0001821923,0.002557604],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.986635,"threshold_uncertainty_score":0.9995885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04344765964728728,"score_gpt":0.3108833747583458,"score_spread":0.2674357151110585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}