{"id":"W4223903024","doi":"10.1097/xcs.0000000000000115","title":"Gene Expression Profiling: Identification of Novel Pathways and Potential Biomarkers in Severe Acute Pancreatitis","year":2022,"lang":"en","type":"article","venue":"Journal of the American College of Surgeons","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Foundation for Healthcare Improvement; Canadian Institutes of Health Research; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Acute pancreatitis; Pancreatitis; Sepsis; Pathogenesis; Gene expression profiling; Gene expression; Gene; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003214648,0.00036962,0.0005818972,0.0007872303,0.0002112084,0.0006311733,0.0001608509,0.0003057527,0.0007628466],"category_scores_gemma":[0.0003641823,0.0001108123,0.0004709725,0.00125279,0.0002247517,0.0002769193,0.0003859453,0.0004060126,0.0002275783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002174366,"about_ca_system_score_gemma":0.0002658625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002407168,"about_ca_topic_score_gemma":0.0004369564,"domain_scores_codex":[0.99976,0.00004888637,0.00002013469,0.00007427366,0.00005018074,0.00004651009],"domain_scores_gemma":[0.9997523,0.00005591908,0.0001023286,0.00001342277,0.00004285372,0.00003301187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003738771,0.0003259617,0.4283806,0.001973463,0.0004988071,0.0007071714,0.0003550656,0.002703538,0.4663715,0.0004388487,0.001735393,0.09277078],"study_design_scores_gemma":[0.0000665947,0.001029055,0.9428673,0.0001768677,0.0004045099,0.001228001,0.0007448798,0.007843452,0.03753531,0.001645346,0.006416139,0.00004247445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841531,0.007373018,0.003561403,0.0003527972,0.00003416753,0.00005603161,0.003599453,0.00005752021,0.0008125303],"genre_scores_gemma":[0.985499,0.004073344,0.005170689,0.0003224483,0.00005786359,0.000115735,0.004139679,0.000013337,0.0006078707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007872303,"threshold_uncertainty_score":0.002551973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013905843033252,"score_gpt":0.2514883249838741,"score_spread":0.2375824819506221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}