{"id":"W4223921537","doi":"10.1007/s12032-022-01702-2","title":"Telomerase gene therapy: a remission toward cancer","year":2022,"lang":"en","type":"review","venue":"Medical Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Telomerase; Telomere; Cancer; Telomerase reverse transcriptase; Biology; Cancer research; Cancer cell; Telomerase RNA component; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008048111,0.0008970577,0.001618971,0.001521217,0.0003013248,0.001140841,0.000893275,0.001476495,0.004255229],"category_scores_gemma":[0.001024653,0.0002111199,0.0004618942,0.00156509,0.000562061,0.001339407,0.0007451288,0.00330333,0.002185257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000665065,"about_ca_system_score_gemma":0.00098127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007615453,"about_ca_topic_score_gemma":0.002137539,"domain_scores_codex":[0.9998227,0.00004335704,0.00001920983,0.00003127978,0.00006258896,0.00002096391],"domain_scores_gemma":[0.999637,0.0002160707,0.00003637805,0.00001127172,0.00006605828,0.00003325324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001318913,0.00009258751,0.0001113558,0.01323469,0.00008397762,0.000118092,0.00004611558,0.0003275785,0.001325233,0.008019635,0.07331491,0.903194],"study_design_scores_gemma":[0.00004974837,0.00009388866,0.000333714,0.003344548,0.0001072921,0.0004522129,0.00003454926,0.00007028792,0.0002406265,0.002525383,0.9927351,0.00001256045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000415133,0.9984297,0.00007770758,0.0004301937,0.0003984698,0.000002475526,0.00001219185,0.000005491472,0.0006020951],"genre_scores_gemma":[0.0003986301,0.997982,0.0001065581,0.0005107871,0.0003991113,0.000005070766,0.00002108041,0.000001458915,0.0005752307],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004255229,"threshold_uncertainty_score":0.0142352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1921261202198647,"score_gpt":0.4605155089703968,"score_spread":0.2683893887505321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}