{"id":"W4223946497","doi":"10.1136/bmjgh-2021-007826","title":"Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or <i>Lactobacillus reuteri</i> DSM 17938: a multicentre, randomised, controlled, factorial trial in Botswana","year":2022,"lang":"en","type":"article","venue":"BMJ Global Health","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; University of British Columbia; Impact","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Government of Canada; Grand Challenges Canada; Hamilton Health Sciences; bioMérieux; University of Pennsylvania","keywords":"Lactobacillus reuteri; Medicine; Placebo; Randomized controlled trial; Intention-to-treat analysis; Internal medicine; Pediatrics; Probiotic","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001913344,0.0002770686,0.001203143,0.00009704925,0.0003163914,0.00003574408,0.0001663059,0.00005314673,0.00005185575],"category_scores_gemma":[0.0004155472,0.0001833618,0.0001975765,0.000287323,0.000164043,0.00008327704,0.0003228438,0.000343258,5.930403e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005566304,"about_ca_system_score_gemma":0.0006652806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062886,"about_ca_topic_score_gemma":0.000122061,"domain_scores_codex":[0.9958836,0.00115807,0.001033836,0.0004795442,0.0005166923,0.0009282187],"domain_scores_gemma":[0.9983808,0.0002332658,0.0003530638,0.0003332113,0.00004406131,0.0006556011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9484252,0.001055601,0.00451605,0.0003517749,0.0004794416,0.0008484694,0.0002227,0.0003345489,0.00002847483,0.000120192,0.0007168184,0.04290068],"study_design_scores_gemma":[0.9462764,0.007247872,0.0322762,0.0003465346,0.0004535611,0.0003135538,0.001188402,0.01088707,0.000001122867,0.0001242154,0.0006595494,0.0002254647],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777775,0.00360758,0.0002592122,0.005338979,0.0004681662,0.01134293,0.0007929291,0.00003477482,0.0003778862],"genre_scores_gemma":[0.9931533,0.004069642,0.0008044556,0.001171905,0.0003199546,0.0003557994,0.00005943677,0.00001878222,0.0000467184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04267522,"threshold_uncertainty_score":0.7477278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03988715236869855,"score_gpt":0.3895889379697774,"score_spread":0.3497017856010789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}