{"id":"W4223946497","doi":"10.1136/bmjgh-2021-007826","title":"Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or <i>Lactobacillus reuteri</i> DSM 17938: a multicentre, randomised, controlled, factorial trial in Botswana","year":2022,"lang":"en","type":"article","venue":"BMJ Global Health","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; University of British Columbia; Impact","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Government of Canada; Grand Challenges Canada; Hamilton Health Sciences; bioMérieux; University of Pennsylvania","keywords":"Lactobacillus reuteri; Medicine; Placebo; Randomized controlled trial; Intention-to-treat analysis; Internal medicine; Pediatrics; Probiotic","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003216393,0.0009377743,0.001678061,0.000467029,0.0004157799,0.0009380592,0.0008318825,0.001332453,0.004305189],"category_scores_gemma":[0.002683961,0.0005061019,0.002289731,0.0003976465,0.0008286901,0.0005853764,0.000657278,0.001033548,0.0003349102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001047883,"about_ca_system_score_gemma":0.001673947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002018772,"about_ca_topic_score_gemma":0.00357621,"domain_scores_codex":[0.9985681,0.0009052485,0.0001274066,0.0001308748,0.0001021884,0.0001662986],"domain_scores_gemma":[0.998774,0.0003917311,0.0004297334,0.00005892951,0.00008158497,0.0002640994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9123347,0.01694328,0.001070457,0.006592239,0.002094255,0.00008015882,0.0002274215,0.0009857935,0.006843113,0.0002778686,0.0004967349,0.05205401],"study_design_scores_gemma":[0.7636859,0.2288458,0.003449479,0.0004866547,0.001197355,0.00002904402,0.00007175368,0.0003173263,0.000695974,0.0001547972,0.001045044,0.0000209288],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773245,0.008981884,0.00086446,0.000867198,0.0006043349,0.009628774,0.0003400359,0.00005178239,0.001337024],"genre_scores_gemma":[0.9776883,0.004412166,0.004243897,0.0006549527,0.0002516034,0.0112454,0.0001891013,0.00001068466,0.001303931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004305189,"threshold_uncertainty_score":0.01701009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03988715236869855,"score_gpt":0.3895889379697774,"score_spread":0.3497017856010789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}