{"id":"W4223948344","doi":"10.1038/s41419-022-04813-w","title":"Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Associazione Italiana per la Ricerca sul Cancro; Fondazione Telethon; University of South Australia; Deutsche Forschungsgemeinschaft; Department of Science and Technology, Ministry of Science and Technology, India; JSS College of Pharmacy; Australian Cancer Research Foundation; Fondazione Umberto Veronesi; Neurosurgical Research Foundation","keywords":"Cancer; Cancer research; Cancer cell; Cell biology; Biology; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006280057,0.0001790109,0.0002295553,0.0001350098,0.0001458295,0.0001954274,0.0001285768,0.0002685555,0.0008027821],"category_scores_gemma":[0.00005563442,0.00009787478,0.000149416,0.0001128259,0.000122846,0.0001339188,0.0001762151,0.0003469002,0.0002953122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002805507,"about_ca_system_score_gemma":0.0001427903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006826216,"about_ca_topic_score_gemma":0.0008572878,"domain_scores_codex":[0.9999422,0.000007394216,0.000004193576,0.00001073998,0.00001109893,0.0000244349],"domain_scores_gemma":[0.9999748,0.000002356133,0.000006561068,0.00000369921,0.000004116649,0.000008378531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001280638,0.00002732853,0.0001328184,0.00002065031,0.000003003314,0.00003053207,0.000005802947,0.0000885789,0.9983264,0.00007569788,0.00005839,0.001102878],"study_design_scores_gemma":[0.00004060858,0.0004190401,0.0052313,0.000005121926,0.000009395999,0.0003590525,0.00002527511,0.001399636,0.9885846,0.00004345407,0.003876806,0.000005648182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948465,0.001379326,0.001453389,0.0001737662,0.00002473427,0.00003791816,0.0003262741,0.00008000846,0.001678129],"genre_scores_gemma":[0.9966859,0.0004098678,0.001024107,0.00007573222,0.000003196586,0.00002526412,0.0003814683,0.000007942796,0.001386467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008027821,"threshold_uncertainty_score":0.002685606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01508863008649056,"score_gpt":0.2614749669088657,"score_spread":0.2463863368223751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}