{"id":"W4223999221","doi":"10.1101/2022.04.01.486593","title":"Newfoundland and Labrador: A mosaic founder population of an Irish and British diaspora from 300 years ago","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; European Regional Development Fund; Science Foundation Ireland; National University of Ireland","keywords":"Founder effect; Population; Geography; Genealogy; Ancient DNA; Irish; Ethnology; Population bottleneck; Isolation by distance; Genetic structure; Demography; Evolutionary biology; History; Haplotype; Biology; Genetic variation; Genetics; Microsatellite; Allele; Sociology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000343474,0.0002239848,0.0003904151,0.0007256479,0.001803556,0.001042518,0.0007078734,0.0002293586,0.002822642],"category_scores_gemma":[0.0004989352,0.0001484196,0.0002469419,0.001211217,0.0008168455,0.0002917998,0.0007817486,0.0004705227,0.0003612324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003385369,"about_ca_system_score_gemma":0.002313072,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.7284827,"about_ca_topic_score_gemma":0.8887864,"domain_scores_codex":[0.9996086,0.00003453513,0.00001519534,0.0001537081,0.00005226783,0.0001355891],"domain_scores_gemma":[0.9994988,0.00005723065,0.0001339218,0.00005746385,0.0001064635,0.0001460016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003769185,0.0001093301,0.9554474,0.00006038616,0.0001398645,0.002175847,0.006308521,0.0001379546,0.009184661,0.0003474217,0.002997287,0.02271448],"study_design_scores_gemma":[0.000009186534,0.00003192563,0.9936827,0.00003985284,0.00003230861,0.0005907999,0.003127003,0.00007904125,0.0002317398,0.00003146578,0.002132408,0.00001141129],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969109,0.0001659569,0.0002051874,0.0001844682,0.000007723423,0.00001795732,0.0009668386,0.00001219803,0.001528909],"genre_scores_gemma":[0.996971,0.0001294511,0.0003667465,0.0001886792,0.00000738394,0.00001483352,0.0007629941,0.00001023509,0.001548574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2715173,"threshold_uncertainty_score":0.5462326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100894988372289,"score_gpt":0.232024648676897,"score_spread":0.2210156987931741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}