{"id":"W4224008869","doi":"10.1016/j.jbc.2022.101937","title":"Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; International Microbiome Centre, University of Calgary; Cumming School of Medicine, University of Calgary","keywords":"DNA; Double stranded; Resection; Chemistry; Molecular biology; Cell biology; Biology; Biochemistry; Medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001700701,0.0004042714,0.0004345052,0.0001707739,0.0002129694,0.0004401315,0.0003731964,0.0003526075,0.001284451],"category_scores_gemma":[0.0001682454,0.0002320326,0.0003783473,0.0001091806,0.0002144471,0.0002668735,0.000345053,0.0006402196,0.0006188072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003647484,"about_ca_system_score_gemma":0.0002474621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005652453,"about_ca_topic_score_gemma":0.00115082,"domain_scores_codex":[0.9998281,0.00001924342,0.00001851988,0.00004855339,0.00004648829,0.00003917257],"domain_scores_gemma":[0.9998914,0.00001723907,0.00002724946,0.0000140907,0.00001090829,0.00003900439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004882738,0.00001732821,0.0001380295,0.00002716124,0.000005187963,0.00001722251,0.000005257419,0.00004697171,0.9992452,0.0000554092,0.00002087281,0.0003725636],"study_design_scores_gemma":[0.000008931062,0.00007911105,0.004548929,0.000002912494,0.000009412394,0.0001502029,0.000009192954,0.001028202,0.992365,0.00002445073,0.001769918,0.000003800036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893205,0.003381685,0.004818313,0.0001074637,0.00004685749,0.00002316011,0.0003568507,0.0001365274,0.001808635],"genre_scores_gemma":[0.9918327,0.001036727,0.00264702,0.00006377071,0.000008937873,0.00002652929,0.000711488,0.00003429777,0.003638419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001284451,"threshold_uncertainty_score":0.004296899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716273175785333,"score_gpt":0.2493129952028479,"score_spread":0.2321502634449946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}