{"id":"W4224033782","doi":"10.1016/j.prp.2022.153892","title":"Evaluation of TERT mRNA expression using RNAscope®: A potential histopathologic diagnostic and prognostic tool","year":2022,"lang":"en","type":"article","venue":"Pathology - Research and Practice","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"National Cancer Institute","keywords":"In situ hybridization; Molecular biology; Messenger RNA; Pathology; Biology; Immunohistochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001232841,0.0004298585,0.0003043381,0.002519042,0.0001759483,0.0005362222,0.0002084048,0.0004250653,0.003056687],"category_scores_gemma":[0.001059897,0.0002339593,0.0002621099,0.0008582666,0.0002973407,0.0003525772,0.0002395968,0.0004324836,0.000948827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001035543,"about_ca_system_score_gemma":0.0001431199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002801015,"about_ca_topic_score_gemma":0.0006092867,"domain_scores_codex":[0.9995953,0.000107619,0.00004271847,0.00008309069,0.0001400189,0.00003125004],"domain_scores_gemma":[0.999054,0.0004211492,0.0001597298,0.00005785401,0.000244675,0.00006259483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005850545,0.00007347481,0.0643038,0.0003207682,0.00008212106,0.0005721686,0.00017694,0.0001973931,0.8849378,0.000246078,0.0005608596,0.04794367],"study_design_scores_gemma":[0.00008635874,0.001299508,0.3995889,0.0001506928,0.0005032928,0.008127041,0.0005279536,0.01126769,0.5669074,0.0009324455,0.01051523,0.00009350322],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8977392,0.009481576,0.07021766,0.0003128508,0.000174368,0.00036697,0.00278098,0.001653216,0.01727323],"genre_scores_gemma":[0.868906,0.005908751,0.1085499,0.000389583,0.000198353,0.0005249436,0.002470503,0.0002422141,0.01280978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003056687,"threshold_uncertainty_score":0.01022559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1814971759555593,"score_gpt":0.4406175413364268,"score_spread":0.2591203653808675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}