{"id":"W4224035361","doi":"10.1016/j.xhgg.2022.100107","title":"Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas","year":2022,"lang":"en","type":"article","venue":"Human Genetics and Genomics Advances","topic":"Tracheal and airway disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Genetics; Phenotype; Foregut; Gene; Bioinformatics; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006581283,0.0003908489,0.0004788721,0.0006595998,0.0002742036,0.0004277858,0.0003881027,0.0004384349,0.001432172],"category_scores_gemma":[0.001921293,0.0001490602,0.0009714127,0.0006236164,0.0002250056,0.0001337172,0.0003234353,0.0002797449,0.0001722612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002025064,"about_ca_system_score_gemma":0.0005596491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002562306,"about_ca_topic_score_gemma":0.001999434,"domain_scores_codex":[0.9997196,0.0001002136,0.00002400576,0.00008315025,0.00004368301,0.00002935939],"domain_scores_gemma":[0.9994048,0.000369773,0.0000967443,0.00003325941,0.00003031057,0.00006513255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001722854,0.0001928203,0.8146963,0.0002044805,0.000852032,0.006638006,0.0002203848,0.02670401,0.120735,0.002231042,0.0004518451,0.0253513],"study_design_scores_gemma":[0.0002531518,0.000551736,0.7913796,0.00007635405,0.0009118617,0.007200341,0.0003028467,0.1689363,0.02601197,0.001970739,0.00234819,0.00005687999],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954337,0.0002054069,0.003750332,0.00003408619,0.000006173703,0.00001663574,0.0003499628,0.00003037111,0.000173285],"genre_scores_gemma":[0.9953869,0.0001330197,0.003813841,0.00001439099,0.000003261385,0.00001274793,0.0004765253,0.00001119212,0.0001482016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002562306,"threshold_uncertainty_score":0.005094767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008304521330814055,"score_gpt":0.240661855749508,"score_spread":0.2323573344186939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}