{"id":"W4224110344","doi":"10.1101/2022.04.01.486735","title":"Actin turnover required for adhesion-independent bleb migration","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University; Case Western Reserve University","keywords":"Bleb (medicine); Cell migration; Cell cortex; Cytoplasm; Actin; Adhesion; Viscoelasticity; Cell; Cell adhesion; Biophysics; Focal adhesion; Cell biology; Chemistry; Cytoskeleton; Materials science; Biology; Neuroscience; Composite material","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001460296,0.0001863144,0.0002939216,0.0001832121,0.0003870575,0.000683182,0.0002064833,0.0004702046,0.00229175],"category_scores_gemma":[0.0007400125,0.0002343158,0.0001615705,0.0001007797,0.0002911418,0.0002584375,0.0002367811,0.0005021727,0.0004763104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003948846,"about_ca_system_score_gemma":0.0002142239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007759613,"about_ca_topic_score_gemma":0.0005631128,"domain_scores_codex":[0.9998697,0.00001771995,0.000006816401,0.00002815612,0.00003797705,0.00003961232],"domain_scores_gemma":[0.9996465,0.0001147544,0.00008174125,0.00003538088,0.00002947845,0.00009215165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002137306,0.00009439959,0.001868204,0.00006362548,0.000008903056,0.0002501752,0.00003397533,0.008951025,0.9844825,0.002262293,0.0002654307,0.001505675],"study_design_scores_gemma":[0.00008951488,0.0001728679,0.01905818,0.00002457597,0.00001112334,0.0005055125,0.0001541354,0.3172204,0.65852,0.002715738,0.001483349,0.00004456321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958461,0.0001438412,0.002969479,0.00005916103,0.00001632647,0.000009451413,0.00006534917,0.00004355631,0.0008466216],"genre_scores_gemma":[0.998796,0.00004136197,0.0006271373,0.000008829835,0.000002491646,0.000009473716,0.0001048536,0.00001679083,0.0003929921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00229175,"threshold_uncertainty_score":0.007666647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526579879864734,"score_gpt":0.2407695107269435,"score_spread":0.2255037119282962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}