{"id":"W4224136952","doi":"10.1101/2022.04.04.486992","title":"Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Ciliogenesis; Centriole; Cell biology; Centrosome; Ciliopathy; Biology; Cilium; Microtubule; Genetics; Cell; Cell cycle; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495283,0.0002170948,0.0001470527,0.0002578058,0.000203004,0.0003934433,0.000181006,0.0002639264,0.003008325],"category_scores_gemma":[0.00015345,0.0001740275,0.000160469,0.0001200547,0.0002459602,0.0002251846,0.0003158413,0.0005220539,0.0009333374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004740515,"about_ca_system_score_gemma":0.0002719155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006392222,"about_ca_topic_score_gemma":0.00110628,"domain_scores_codex":[0.9999164,0.000007828552,0.000004967647,0.00001901195,0.00003141674,0.00002019789],"domain_scores_gemma":[0.9998384,0.00002790173,0.00004047277,0.00002688406,0.00001474799,0.00005151916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001011819,0.00001548598,0.0008080023,0.00003946088,0.000002746276,0.00008116321,0.00001815921,0.0001338031,0.9964262,0.0004785842,0.0001962557,0.001699007],"study_design_scores_gemma":[0.00001771551,0.0000557746,0.01089133,0.000006207967,0.000003296592,0.0001611733,0.00003182101,0.0009367191,0.9841532,0.0001365619,0.003603185,0.000003006721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902717,0.00109447,0.00376415,0.0002416318,0.00005554221,0.00001860074,0.0006804619,0.0002808967,0.003592621],"genre_scores_gemma":[0.9910399,0.0004059331,0.002171306,0.00004605362,0.00001415218,0.00001284512,0.0005071706,0.00005321212,0.005749335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003008325,"threshold_uncertainty_score":0.01006389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009661738872433627,"score_gpt":0.2187396352494665,"score_spread":0.2090778963770328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}