{"id":"W4224144883","doi":"10.21203/rs.3.rs-1523595/v1","title":"Efficacy and toxicity of combined inhibition of EGFR and VEGF in patients with advanced non-small-cell lung cancer harboring activating EGFR mutations: A systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Research Square","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Meta-analysis; Lung cancer; VEGF receptors; Toxicity; Oncology; Medicine; Epidermal growth factor receptor; EGFR inhibitors; Cancer research; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003143707,0.001521765,0.01016882,0.001586341,0.0002259564,0.001422341,0.001164955,0.001347176,0.00291845],"category_scores_gemma":[0.006286252,0.0008815583,0.02084963,0.002404438,0.0004149068,0.0008990278,0.0007690763,0.001651928,0.0002265411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001234477,"about_ca_system_score_gemma":0.001183394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003787141,"about_ca_topic_score_gemma":0.01364986,"domain_scores_codex":[0.9983936,0.000617334,0.0004675341,0.0002390052,0.0001924233,0.00009012561],"domain_scores_gemma":[0.9974437,0.001656545,0.0006033808,0.000083644,0.0001518359,0.00006103487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.009179165,0.00008842375,0.00454487,0.3395386,0.6098753,0.0001355133,0.00009238677,0.001024009,0.0008573962,0.0001638061,0.001166762,0.03333383],"study_design_scores_gemma":[0.002469893,0.000659771,0.004951018,0.01054739,0.9781263,0.00009801926,0.00004899115,0.000189073,0.0001591691,0.0001696366,0.002549286,0.00003150162],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009603943,0.9891694,0.0002578868,0.000106623,0.0001134809,0.0001021361,0.0003728232,0.00001693948,0.0002567866],"genre_scores_gemma":[0.2368408,0.7595853,0.001080157,0.001021459,0.0001837738,0.0002538282,0.0005597717,0.00002100916,0.0004538998],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01016882,"threshold_uncertainty_score":0.01662576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07069963616731054,"score_gpt":0.4343506532759887,"score_spread":0.3636510171086781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}