{"id":"W4224221548","doi":"10.1038/s41408-022-00668-8","title":"Venetoclax combinations delay the time to deterioration of HRQoL in unfit patients with acute myeloid leukemia","year":2022,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Genentech; AbbVie","keywords":"Medicine; Quality of life (healthcare); Internal medicine; Cytarabine; Placebo; Myeloid leukemia; Visual analogue scale; Oncology; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004315206,0.0001208812,0.0002374675,0.0002648617,0.0002842052,0.00002975402,0.0002767347,0.00003485153,0.001060414],"category_scores_gemma":[0.00003836886,0.00008424003,0.00005536582,0.000732022,0.00005437019,0.0001073247,0.0001327197,0.000741308,0.00001769937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002319776,"about_ca_system_score_gemma":0.002679831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001887073,"about_ca_topic_score_gemma":0.00006774978,"domain_scores_codex":[0.9982289,0.0001552459,0.0003452222,0.0001654909,0.0008129886,0.0002921473],"domain_scores_gemma":[0.9990813,0.00005257369,0.0001821266,0.0002347801,0.0003027372,0.0001465181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01812266,0.00459259,0.5660102,0.0002309786,0.005402052,0.002317759,0.01667786,0.05773838,0.1183285,0.0003719833,0.09399683,0.1162102],"study_design_scores_gemma":[0.06074679,0.01630984,0.8557125,0.0006684293,0.001570733,0.00291536,0.0009698566,0.007243062,0.01072007,0.0004490047,0.04173838,0.0009560197],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964409,0.0001690752,0.0000613474,0.002121122,0.00007398422,0.0006757152,0.00005898829,0.000009836278,0.0003890363],"genre_scores_gemma":[0.9973413,0.00006004727,0.0004142402,0.0007380261,0.00009758102,0.0002107797,0.00002767872,0.00003190607,0.001078454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2897022,"threshold_uncertainty_score":0.9998528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008543927453387928,"score_gpt":0.2656750802293543,"score_spread":0.2571311527759664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}