{"id":"W4224234032","doi":"10.1002/ijc.34015","title":"Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases","year":2022,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Heart, Lung, and Blood Institute; School of Public Health, Imperial College London; Instituto de Salud Carlos III; National Health and Medical Research Council; Centers for Disease Control and Prevention; National Institutes of Health; Insamlingsstiftelsen Diabetes Wellness Network Sverige; Health Research Fund of Central Denmark Region; Mutuelle Générale de l'Education Nationale; Institut Gustave-Roussy; Medical Research Council; Medical Research Council Canada; Cancer Council Victoria; Deutsche Krebshilfe; Associazione Italiana per la Ricerca sul Cancro; Umeå Universitet; Vetenskapsrådet; Canadian Institutes of Health Research; Cancerfonden; Institut National de la Santé et de la Recherche Médicale; Ministerul Cercetării şi Inovării; Imperial College London; Ontario Ministry of Research and Innovation; Deutsches Krebsforschungszentrum; Ligue Contre le Cancer; Bundesministerium für Bildung und Forschung; Harvard T.H. Chan School of Public Health; National Institute for Health and Care Research; American Cancer Society; VicHealth; World Cancer Research Fund; Danish Cancer Society Research Center; Génome Québec; National Cancer Institute; Knut och Alice Wallenbergs Stiftelse; Fred Hutchinson Cancer Research Center; Johns Hopkins University; Kræftens Bekæmpelse; Canadian Cancer Society Research Institute; McGill University; Brigham and Women's Hospital; World Health Organization; Cancer Research UK; NIHR Imperial Biomedical Research Centre; Centre International de Recherche sur le Cancer; U.S. Department of Health and Human Services","keywords":"Colorectal cancer; Oncology; Internal medicine; Medicine; KRAS; Diabetes mellitus; Microsatellite instability; Cancer; Epidemiology; Allele; Biology; Endocrinology; Genetics; Microsatellite; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004562041,0.0008477991,0.002528034,0.002724406,0.0004171791,0.001128578,0.0006384447,0.0008178448,0.001208264],"category_scores_gemma":[0.006058303,0.001028578,0.005302833,0.004574168,0.000240782,0.0004941153,0.0007517483,0.0004542644,0.0001901345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003663241,"about_ca_system_score_gemma":0.0003165057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007165105,"about_ca_topic_score_gemma":0.008358786,"domain_scores_codex":[0.9960935,0.00166666,0.0006904848,0.0009477815,0.0004216866,0.0001799301],"domain_scores_gemma":[0.9952615,0.001723739,0.001508504,0.0008641676,0.0004602134,0.0001818476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002460589,0.00003809557,0.9504555,0.0004663703,0.04171255,0.000137673,0.00003734613,0.0003359304,0.0005353807,0.00002518576,0.0004628848,0.003332534],"study_design_scores_gemma":[0.0002469684,0.0003546673,0.9587204,0.0001101759,0.03774862,0.0003272591,0.00009066512,0.001170511,0.0002210989,0.00007676962,0.0009116514,0.00002119694],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9540144,0.03624525,0.002613668,0.00008808123,0.0001051659,0.00009348823,0.006035355,0.00006092568,0.0007436566],"genre_scores_gemma":[0.9939985,0.002588899,0.0006346533,0.00005782893,0.00007110719,0.00007373129,0.00236557,0.00001472624,0.0001949072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007165105,"threshold_uncertainty_score":0.02412665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006227953973449415,"score_gpt":0.2802264162948674,"score_spread":0.2739984623214179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}