{"id":"W4224250473","doi":"10.1101/2022.04.05.487096","title":"Genomic signatures of selection associated with benzimidazole drug treatments in <i>Haemonchus contortus</i> field populations","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Helminth infection and control","field":"Veterinary","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Haemonchus contortus; Population; Genetics; Genome; Single-nucleotide polymorphism; Evolutionary biology; Genotype; Gene; Nematode; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001875936,0.0001743845,0.0002306369,0.0005293929,0.0001675636,0.0002455015,0.0001886029,0.0002504519,0.0008015048],"category_scores_gemma":[0.000313122,0.0001414781,0.0001974686,0.0004001925,0.0001872049,0.0001100361,0.0002005881,0.0003083119,0.0001237754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002562579,"about_ca_system_score_gemma":0.0001145448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002495336,"about_ca_topic_score_gemma":0.00644703,"domain_scores_codex":[0.9998397,0.00002132695,0.000008961139,0.00007620115,0.00002989563,0.00002396344],"domain_scores_gemma":[0.9996779,0.00008755508,0.0001194743,0.0000203067,0.00005486712,0.00003986429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002813099,0.00005329383,0.07320739,0.00006641512,0.00007542533,0.0001231529,0.0002826051,0.0002791811,0.9197626,0.00005622545,0.0001314505,0.005680866],"study_design_scores_gemma":[0.00001071052,0.0001766804,0.9846644,0.000005793212,0.00003176612,0.0001792784,0.0001495967,0.0005454902,0.01359328,0.00002348187,0.0006111462,0.000008313323],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985233,0.00007519055,0.0005365576,0.00000936602,0.000001655365,0.000009933035,0.000515756,0.00001554511,0.0003127325],"genre_scores_gemma":[0.9966019,0.00004968306,0.001260928,0.00004615085,0.000003150126,0.00002548517,0.001573745,0.00001483938,0.0004240397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002495336,"threshold_uncertainty_score":0.004961669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505036965158918,"score_gpt":0.2616341007042453,"score_spread":0.2365837310526561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}