{"id":"W4224251450","doi":"10.1016/j.jtho.2022.03.014","title":"Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations","year":2022,"lang":"en","type":"review","venue":"Journal of Thoracic Oncology","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"ARC Training Centre in Lightweight Automotive Structures; Janssen Pharmaceuticals; National Institute of Environmental Health Sciences; Medical Research Council; Genentech; Andrew and Jaime Sullivan Family Foundation; National Institutes of Health; Honeywell; Aldeyra Therapeutics; BeiGene; Clovis Oncology; Astex Pharmaceuticals; Bayer Fund; National Health and Medical Research Council; AstraZeneca; Novocure; Merck Sharp and Dohme; University of Hawaiʻi Foundation; Takeda Pharmaceuticals U.S.A.; AbbVie; Medtronic; Roche; Novartis; EMD Serono; Mesothelioma Applied Research Foundation; Merck; GlaxoSmithKline; National Cancer Institute; Bayer; Maurice and Joanna Sullivan Family Foundation; Bristol-Myers Squibb; U.S. Department of Defense; Eli Lilly and Company; Inventiva Pharma; Pfizer; Ariad Pharmaceuticals; Boehringer Ingelheim","keywords":"Medicine; BAP1; Germline; Mesothelioma; Germline mutation; Oncology; Internal medicine; Intensive care medicine; General surgery; Mutation; Genetics; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002754576,0.0003944002,0.0008672176,0.000793032,0.0001625173,0.0004215775,0.0004582574,0.0007347713,0.001125827],"category_scores_gemma":[0.0009339089,0.0001428437,0.0006219871,0.000840436,0.0001538146,0.0003871984,0.000314355,0.0006679928,0.0002918079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002459832,"about_ca_system_score_gemma":0.000554077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001440618,"about_ca_topic_score_gemma":0.003466244,"domain_scores_codex":[0.999842,0.00003943685,0.00002563524,0.00002997086,0.00004306418,0.00001984987],"domain_scores_gemma":[0.9997576,0.000148839,0.00004491243,0.000004031997,0.00002732906,0.00001727815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001715424,0.00004658616,0.004283995,0.01656458,0.0005128259,0.001829478,0.0001052114,0.0003035112,0.001010104,0.0006008215,0.0163523,0.9582189],"study_design_scores_gemma":[0.0003050817,0.0005305606,0.07374579,0.05287394,0.00501221,0.0618865,0.0009199324,0.0006077376,0.0013311,0.003311359,0.799313,0.0001628258],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006595546,0.9985678,0.00006461314,0.0001602535,0.00007915738,0.000002067064,0.00001616487,0.000002124552,0.000448242],"genre_scores_gemma":[0.009638129,0.9892833,0.0002472039,0.0002857281,0.0002328587,0.000005268531,0.00006874163,0.00000103616,0.0002376469],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001440618,"threshold_uncertainty_score":0.003766239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02591016594084832,"score_gpt":0.4073928890563097,"score_spread":0.3814827231154613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}