{"id":"W4224261285","doi":"10.1182/bloodadvances.2021005910","title":"ATG4A regulates human erythroid maturation and mitochondrial clearance","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; University of Toronto; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington; Fred Hutchinson Cancer Research Center","keywords":"Autophagy; Erythropoiesis; Cell biology; Haematopoiesis; Biology; Mitochondrion; Progenitor cell; Stem cell; Myeloid; Immunology; Apoptosis; Biochemistry; Internal medicine; Anemia; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004176813,0.00009191236,0.0001759128,0.00004863385,0.0003257989,0.000009162542,0.00003820873,0.00003062053,0.0003323073],"category_scores_gemma":[0.00001996101,0.00008441664,0.00003963442,0.0001074319,0.00007571867,0.0001061134,0.00004555967,0.0001622516,0.000009836372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001634082,"about_ca_system_score_gemma":0.00001728307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006397163,"about_ca_topic_score_gemma":0.000006583972,"domain_scores_codex":[0.9992931,0.00004957255,0.0001461535,0.0002393901,0.0001398818,0.0001318923],"domain_scores_gemma":[0.9996809,0.00002774361,0.0000703892,0.0001442598,0.00002709647,0.00004964981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001053817,0.0002553055,0.002288145,0.0001071211,0.00005077439,0.00004259757,0.0003533921,0.0001125901,0.9861804,0.002282622,0.001972805,0.005300384],"study_design_scores_gemma":[0.008721801,0.004528156,0.1404453,0.00008092825,0.0002621997,0.001186246,0.001298374,0.0001549062,0.04113319,0.005124377,0.7965446,0.0005199137],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929909,0.003701501,0.00001929162,0.0008264395,0.0007229759,0.0002266972,0.000008930564,0.00009184102,0.00141149],"genre_scores_gemma":[0.9946445,0.0003349341,0.001138405,0.0009045289,0.0006674667,0.00005211128,0.00006800625,0.00001607497,0.002174028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9450473,"threshold_uncertainty_score":0.3638532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009884979490989645,"score_gpt":0.2566982550904163,"score_spread":0.2468132755994267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}