{"id":"W4224261285","doi":"10.1182/bloodadvances.2021005910","title":"ATG4A regulates human erythroid maturation and mitochondrial clearance","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; University of Toronto; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington; Fred Hutchinson Cancer Research Center","keywords":"Autophagy; Erythropoiesis; Cell biology; Haematopoiesis; Biology; Mitochondrion; Progenitor cell; Stem cell; Myeloid; Immunology; Apoptosis; Biochemistry; Internal medicine; Anemia; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000179486,0.0001787148,0.0002010047,0.0002431313,0.000175897,0.0002547819,0.0001622465,0.0001419136,0.001025506],"category_scores_gemma":[0.000122946,0.00007974979,0.0001529333,0.0001308242,0.0001500111,0.0001392211,0.0002089215,0.0002426311,0.0003553082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003698007,"about_ca_system_score_gemma":0.0002810262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005507013,"about_ca_topic_score_gemma":0.0005169316,"domain_scores_codex":[0.9999043,0.00002120002,0.00001154906,0.00001861415,0.0000275833,0.00001675002],"domain_scores_gemma":[0.9999478,0.000008531672,0.00001397687,0.000006454254,0.00001415442,0.000009151473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009917234,0.00001124543,0.0005463199,0.0000382847,0.000005038851,0.0000629724,0.00001481036,0.00006995649,0.9962624,0.0002070486,0.0000902408,0.002592486],"study_design_scores_gemma":[0.00001297232,0.00007356835,0.01092498,0.00000709622,0.00001657878,0.0003779266,0.00002381841,0.0008613919,0.9788309,0.0001726624,0.008694069,0.000004078091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782355,0.009915019,0.006805501,0.0002003766,0.00004408949,0.00005164159,0.0009122796,0.0001531284,0.003682449],"genre_scores_gemma":[0.990014,0.002239408,0.002934479,0.00004344305,0.000009999136,0.00003127895,0.0009655001,0.00002183081,0.003740118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001025506,"threshold_uncertainty_score":0.003430605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009884979490989645,"score_gpt":0.2566982550904163,"score_spread":0.2468132755994267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}