{"id":"W4224264729","doi":"10.3324/haematol.2021.280203","title":"The mutational landscape in chronic myelomonocytic leukemia and its impact on allogeneic hematopoietic cell transplantation outcomes: a Center for Blood and Marrow Transplantation Research (CIBMTR) analysis","year":2022,"lang":"en","type":"article","venue":"Haematologica","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Cancer Institute","keywords":"Medicine; Internal medicine; Chronic myelomonocytic leukemia; Transplantation; KRAS; Hematopoietic stem cell transplantation; Neuroblastoma RAS viral oncogene homolog; International Prognostic Scoring System; Oncology; Hematopoietic cell; Multivariate analysis; Gastroenterology; Bone marrow; Haematopoiesis; Myelodysplastic syndromes; Cancer; Stem cell; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001454744,0.0002248083,0.0005092402,0.0006460845,0.0005991372,0.0000586667,0.000180475,0.0001093324,0.0001539405],"category_scores_gemma":[0.00008388152,0.0001454775,0.0001672243,0.0008425552,0.0001177039,0.00006964294,0.0000476374,0.0005711038,0.000006825248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006757807,"about_ca_system_score_gemma":0.0005135308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005292757,"about_ca_topic_score_gemma":0.0001625181,"domain_scores_codex":[0.9973324,0.0004904552,0.0004190585,0.0005232472,0.0006524702,0.0005823467],"domain_scores_gemma":[0.9976749,0.001746387,0.0000919878,0.0002338822,0.0001045994,0.000148194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02131498,0.001316669,0.9033197,0.006131518,0.003764553,0.006320873,0.01166786,0.0120269,0.02514261,0.004668735,0.001046061,0.00327956],"study_design_scores_gemma":[0.02013917,0.004063719,0.9280553,0.0001380479,0.00186178,0.003974571,0.001914268,0.03216552,0.005986787,0.001013515,0.0001452591,0.0005421042],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952579,0.001388039,0.00008351709,0.001272119,0.00002052016,0.001488609,0.0002192071,0.00002928447,0.0002408572],"genre_scores_gemma":[0.9963316,0.001902663,0.0001130072,0.0001209919,0.00001908889,0.0007745283,0.0005297419,0.00002464163,0.0001837203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02473557,"threshold_uncertainty_score":0.5932401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03740917690042603,"score_gpt":0.3581258702767788,"score_spread":0.3207166933763527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}