{"id":"W4224275281","doi":"10.1002/anse.202200012","title":"Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments","year":2022,"lang":"en","type":"review","venue":"Analysis & Sensing","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aptamer; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Computational biology; Nucleic acid; Isolation (microbiology); Coronavirus; Nanotechnology; Identification (biology); Virology; Biology; Chemistry; Bioinformatics; Medicine; Molecular biology; Biochemistry; Materials science; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006289063,0.00102891,0.0009104151,0.002078886,0.0001937011,0.0008632141,0.0008081741,0.001326293,0.002965303],"category_scores_gemma":[0.0005540684,0.0003948606,0.0004540923,0.001873639,0.0004486176,0.001537637,0.0006402404,0.002105236,0.003066901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006065869,"about_ca_system_score_gemma":0.0007482722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000803235,"about_ca_topic_score_gemma":0.001250584,"domain_scores_codex":[0.9997869,0.00002425699,0.00001825533,0.000042218,0.0001027211,0.00002569634],"domain_scores_gemma":[0.9997868,0.00009134223,0.00002841722,0.000007468738,0.00006380815,0.0000223223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004906697,0.00009978029,0.0001084139,0.009191057,0.00004620555,0.0001441242,0.00004702884,0.000527839,0.007025404,0.005506827,0.02047239,0.9567817],"study_design_scores_gemma":[0.000009742123,0.00009650895,0.0004118196,0.001202348,0.00003537914,0.0007492911,0.0000271132,0.0001078375,0.001619527,0.001324321,0.9944002,0.00001589388],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001873654,0.9972907,0.000390075,0.0002175594,0.0002169821,0.000007743427,0.0000200955,0.00001182191,0.001657763],"genre_scores_gemma":[0.000840192,0.9967609,0.0004473714,0.0002281038,0.0001152273,0.00001154986,0.00003899089,0.000002726025,0.001554902],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002965303,"threshold_uncertainty_score":0.009919941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03222547883306504,"score_gpt":0.3294445023682491,"score_spread":0.297219023535184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}