{"id":"W4224275281","doi":"10.1002/anse.202200012","title":"Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments","year":2022,"lang":"en","type":"review","venue":"Analysis & Sensing","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aptamer; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Computational biology; Nucleic acid; Isolation (microbiology); Coronavirus; Nanotechnology; Identification (biology); Virology; Biology; Chemistry; Bioinformatics; Medicine; Molecular biology; Biochemistry; Materials science; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002617122,0.0003549334,0.0009386664,0.0003373898,0.0003011282,0.00007342237,0.0000823837,0.0002037493,0.000001478193],"category_scores_gemma":[0.0001874834,0.0003145175,0.0003594122,0.0006181091,0.00008433671,0.00000464021,0.0001208043,0.0001089496,2.909334e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003310132,"about_ca_system_score_gemma":0.00007027238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007369613,"about_ca_topic_score_gemma":0.00002956676,"domain_scores_codex":[0.998342,0.000150877,0.0004781161,0.0006791262,0.0001241069,0.0002257425],"domain_scores_gemma":[0.9989902,0.0001565829,0.0004146577,0.0003018496,0.00009002213,0.00004667437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005472562,0.00001167088,0.00006947333,0.0003014301,0.002383827,0.000001830027,0.00002045723,3.015568e-7,0.005084762,0.000004229704,0.00002261192,0.9920939],"study_design_scores_gemma":[0.00008962005,0.00004962959,0.00006500228,0.0001913304,0.008538674,0.00002471879,0.00002125578,0.0003043712,0.001077636,0.00001680309,0.989159,0.0004619323],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004147345,0.9631845,0.03174318,0.00004474526,0.00006002522,0.0006497765,0.0001029634,0.00004865855,0.00001877381],"genre_scores_gemma":[0.008093447,0.9831868,0.004671412,0.0002490988,0.00008392681,0.00001625182,0.003539597,0.00004725445,0.0001121473],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.991632,"threshold_uncertainty_score":0.9999307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03222547883306504,"score_gpt":0.3294445023682491,"score_spread":0.297219023535184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}