{"id":"W4224291314","doi":"10.1093/glycob/cwac023","title":"Chemoenzymatic synthesis of an α-1,6-glucan-based conjugate vaccine against <i>Helicobacter pylori</i>","year":2022,"lang":"en","type":"article","venue":"Glycobiology","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Helicobacter pylori; Glycoconjugate; Glucan; Microbiology; Conjugate vaccine; Chemistry; Bovine serum albumin; Toxoid; Glucosyltransferase; Clarithromycin; Conjugate; Lipopolysaccharide; Biochemistry; Antigen; Biology; Immunization; Immunology; Antibiotics; Streptococcus pneumoniae; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152843,0.0002461441,0.000104956,0.00006779326,0.00005623696,0.000150104,0.0001278318,0.0001813972,0.0004027792],"category_scores_gemma":[0.0001069628,0.00006998607,0.0001378782,0.0001038403,0.0001016507,0.0001586137,0.0001312359,0.0003059556,0.0002009124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001226995,"about_ca_system_score_gemma":0.0001585027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002115672,"about_ca_topic_score_gemma":0.0002846219,"domain_scores_codex":[0.9999323,0.00001679411,0.000004973424,0.00001367957,0.00001612933,0.00001617212],"domain_scores_gemma":[0.999952,0.000005976417,0.00001957171,0.000005537454,0.000007913495,0.00000911625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003087195,0.00002279105,0.00009250459,0.00002987747,0.000003504954,0.00002919466,0.000008947645,0.0001723866,0.9979704,0.0001025496,0.00001231607,0.001524826],"study_design_scores_gemma":[0.00000674373,0.0003422962,0.0005263806,0.000002521529,0.000008602376,0.00008788468,0.000006284594,0.0003432018,0.9974409,0.00002145658,0.00121125,0.000002379376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872636,0.0005935337,0.01052409,0.00006656654,0.00002812123,0.00006341292,0.00008175286,0.00003113033,0.001347756],"genre_scores_gemma":[0.9844582,0.0005184487,0.01331594,0.0000566621,0.00000755079,0.00002116504,0.0002114549,0.00001537487,0.001395114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004027792,"threshold_uncertainty_score":0.001347423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225231190119066,"score_gpt":0.2432927027082619,"score_spread":0.2310403908070712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}