{"id":"W4224292621","doi":"10.3389/ti.2022.10333","title":"Patient Selection for Downstaging of Hepatocellular Carcinoma Prior to Liver Transplantation—Adjusting the Odds?","year":2022,"lang":"en","type":"review","venue":"Transplant International","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"Universität Leipzig; Deutsche Forschungsgemeinschaft","keywords":"Milan criteria; Medicine; Hepatocellular carcinoma; Selection (genetic algorithm); Liver transplantation; Transplantation; Biopsy; General surgery; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002948628,0.0003859176,0.0008419195,0.0003710111,0.0002038514,0.00002698267,0.0002606145,0.0001336016,0.0006942368],"category_scores_gemma":[0.00002329664,0.0002803954,0.0008010836,0.0002969652,0.00003037604,0.00005998531,0.00002315439,0.0003252999,0.00001491508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002691772,"about_ca_system_score_gemma":0.0003000492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001516415,"about_ca_topic_score_gemma":0.00001467437,"domain_scores_codex":[0.9977398,0.0001194629,0.000800322,0.0004578068,0.0005956786,0.0002869239],"domain_scores_gemma":[0.9987958,0.0004650414,0.000298189,0.0002022764,0.0001291512,0.0001095255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006101649,0.0003634951,0.01513085,0.02516504,0.001349765,0.0003993368,0.003659826,0.00001282547,0.00004359884,0.0005754358,0.0002063367,0.9524834],"study_design_scores_gemma":[0.001044427,0.0005852497,0.0001876095,0.004589365,0.005696109,0.001202437,0.00007078959,0.003833183,0.0004897477,0.000006075466,0.9819016,0.0003933701],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02190777,0.96186,0.004683255,0.0002230782,0.0008911655,0.006593187,0.002570167,0.00009448927,0.001176881],"genre_scores_gemma":[0.1044271,0.8890715,0.0008994902,0.00009250051,0.0002436823,0.001483822,0.003480757,0.00007600976,0.0002250384],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9816953,"threshold_uncertainty_score":0.9999648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1031525277302406,"score_gpt":0.2978679098195921,"score_spread":0.1947153820893515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}