{"id":"W4224304689","doi":"10.1016/s2666-5247(22)00043-x","title":"Sustained effect of LACTIN-V (Lactobacillus crispatus CTV-05) on genital immunology following standard bacterial vaginosis treatment: results from a randomised, placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"The Lancet Microbe","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Centre for Global Health Research; St. Michael's Hospital; Toronto General Hospital; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Canadian Cancer Society; Cystic Fibrosis Foundation","keywords":"Bacterial vaginosis; Lactobacillus crispatus; Medicine; Placebo; Internal medicine; Lactobacillus; Metronidazole; Vaginal disease; Vaginal flora; Vagina; Immunology; Obstetrics; Antibiotics; Biology; Surgery; Microbiology; Pathology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002782041,0.0004665734,0.001856206,0.0002724997,0.0008703307,0.00004875799,0.0006458458,0.0002212946,0.001095754],"category_scores_gemma":[0.001880153,0.0003070136,0.0007767099,0.0002999142,0.0002939343,0.00009314576,0.0004360501,0.0009659109,0.0001293127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006878222,"about_ca_system_score_gemma":0.0002791011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001115483,"about_ca_topic_score_gemma":0.00004028786,"domain_scores_codex":[0.9919796,0.005419998,0.0008145639,0.000760159,0.0001596285,0.000866038],"domain_scores_gemma":[0.9927052,0.005419574,0.0004766948,0.001261181,0.0001058667,0.00003146685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6131312,0.0003089991,0.00008124326,0.00000482392,0.002516545,0.0000264217,0.0007218114,0.00002896688,0.3797297,0.00002875658,0.001602289,0.001819344],"study_design_scores_gemma":[0.739557,0.008590098,0.0001087001,0.00001186388,0.000461318,0.00004305467,0.000351329,0.000001534958,0.2347769,0.00006535184,0.01579574,0.0002371006],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839501,0.001128808,0.00001347844,0.0009221867,0.004271389,0.005753222,0.001476576,0.0001280622,0.002356177],"genre_scores_gemma":[0.995402,0.00008890586,0.00001501769,0.00004434543,0.0004772076,0.001350389,0.0006590096,0.00004968354,0.001913384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1449528,"threshold_uncertainty_score":0.9999382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647941430061346,"score_gpt":0.2809894934913375,"score_spread":0.2645100791907241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}