{"id":"W4224304689","doi":"10.1016/s2666-5247(22)00043-x","title":"Sustained effect of LACTIN-V (Lactobacillus crispatus CTV-05) on genital immunology following standard bacterial vaginosis treatment: results from a randomised, placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"The Lancet Microbe","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Centre for Global Health Research; St. Michael's Hospital; Toronto General Hospital; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Canadian Cancer Society; Cystic Fibrosis Foundation","keywords":"Bacterial vaginosis; Lactobacillus crispatus; Medicine; Placebo; Internal medicine; Lactobacillus; Metronidazole; Vaginal disease; Vaginal flora; Vagina; Immunology; Obstetrics; Antibiotics; Biology; Surgery; Microbiology; Pathology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002620358,0.001350439,0.003354836,0.0005584164,0.000436392,0.001170586,0.00105031,0.002743811,0.005726428],"category_scores_gemma":[0.003112291,0.00061994,0.002229086,0.0006048915,0.001251276,0.0009649732,0.0004538565,0.001878929,0.0007372701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007916171,"about_ca_system_score_gemma":0.0009121582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001115325,"about_ca_topic_score_gemma":0.001850823,"domain_scores_codex":[0.9985489,0.0008449721,0.0001597255,0.0001771458,0.0001065027,0.0001626903],"domain_scores_gemma":[0.9982238,0.0006890401,0.0004617104,0.0001331541,0.0001381381,0.0003540384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9811389,0.003881881,0.0003334391,0.001436117,0.001090372,0.00002915887,0.00004117056,0.00009177474,0.002128532,0.00002808319,0.0001888808,0.009611626],"study_design_scores_gemma":[0.9119933,0.08441265,0.001848377,0.00009613523,0.0007884111,0.00002246633,0.00002695905,0.0001052776,0.0003082952,0.00005778617,0.0003289305,0.00001137441],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738056,0.01769574,0.0005287079,0.0005524012,0.0007493129,0.004387992,0.0008118266,0.0001036561,0.001364674],"genre_scores_gemma":[0.9850591,0.006680299,0.0009695942,0.0006833779,0.0006876285,0.003739062,0.0006726202,0.00001772209,0.001490506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005726428,"threshold_uncertainty_score":0.01915681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647941430061346,"score_gpt":0.2809894934913375,"score_spread":0.2645100791907241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}