{"id":"W4224309069","doi":"10.3390/membranes12040397","title":"Protein Profiling of Malaria-Derived Extracellular Vesicles Reveals Distinct Subtypes","year":2022,"lang":"en","type":"article","venue":"Membranes","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"McGill University Health Centre; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Plasmodium falciparum; Biogenesis; Plasmodium (life cycle); Cell biology; Intracellular parasite; Malaria; Extracellular vesicles; Differential centrifugation; Extracellular; Intracellular; Parasite hosting; Immunology; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432279,0.0002197188,0.0002170894,0.0004855208,0.0002001495,0.0004019427,0.0001207485,0.0002677773,0.0004534351],"category_scores_gemma":[0.0002278822,0.000108349,0.0002011042,0.0002827839,0.0001387529,0.000223711,0.0002744992,0.0002792554,0.000315973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574747,"about_ca_system_score_gemma":0.00009997606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004127371,"about_ca_topic_score_gemma":0.0003875293,"domain_scores_codex":[0.9998804,0.00001456332,0.000009708686,0.00003232925,0.0000245448,0.00003848028],"domain_scores_gemma":[0.9999253,0.0000140593,0.00001632806,0.000005744329,0.00002194718,0.00001664794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000130369,0.000007950049,0.001166553,0.00003236335,0.000006196241,0.00004509025,0.00003130387,0.00002725813,0.9974056,0.00006535133,0.00003593362,0.001046102],"study_design_scores_gemma":[0.00001112235,0.0002289403,0.1344198,0.00002800164,0.00005535828,0.001165113,0.0002994028,0.004069485,0.8548456,0.0002341597,0.004621432,0.00002162835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993632,0.00114249,0.003340502,0.0000579236,0.0000134987,0.00002267936,0.001051345,0.00002901661,0.0007104842],"genre_scores_gemma":[0.9897298,0.001094877,0.004777435,0.00007949545,0.00001181761,0.00004163197,0.002755559,0.00003609691,0.001473399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004855208,"threshold_uncertainty_score":0.001516938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01115985325854921,"score_gpt":0.2315833178563555,"score_spread":0.2204234645978063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}