{"id":"W4224309069","doi":"10.3390/membranes12040397","title":"Protein Profiling of Malaria-Derived Extracellular Vesicles Reveals Distinct Subtypes","year":2022,"lang":"en","type":"article","venue":"Membranes","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"McGill University Health Centre; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Plasmodium falciparum; Biogenesis; Plasmodium (life cycle); Cell biology; Intracellular parasite; Malaria; Extracellular vesicles; Differential centrifugation; Extracellular; Intracellular; Parasite hosting; Immunology; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004648375,0.0001899443,0.0002155485,0.00005208846,0.0001924824,0.0000159758,0.0004083453,0.00007273936,0.0001716923],"category_scores_gemma":[0.0001671572,0.0002002848,0.0001470008,0.0001389249,0.0001217618,0.000005599752,0.0003234906,0.0001360511,0.000006137908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001569688,"about_ca_system_score_gemma":0.00008393007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001440791,"about_ca_topic_score_gemma":0.000005481033,"domain_scores_codex":[0.9983959,0.0002508083,0.0003624822,0.0004274386,0.0002859283,0.0002774615],"domain_scores_gemma":[0.9990634,0.00001808457,0.0002043251,0.0005624522,0.00006523604,0.00008648267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002314155,0.0001801946,0.003743412,0.0002150551,0.00004773047,0.00003166808,0.00005770304,0.000229562,0.9942426,0.0005283468,0.00009405179,0.0003982734],"study_design_scores_gemma":[0.0004448656,0.0001785569,0.001961365,0.00001500199,0.00003344323,0.00001879545,0.0002236345,0.00009831987,0.9932525,0.0004163799,0.003121159,0.0002359609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928684,0.005636628,0.00028681,0.0001210446,0.0001061154,0.0005616602,0.00008259195,0.00003121176,0.0003056012],"genre_scores_gemma":[0.9960786,0.00001774132,0.001916003,0.00003354592,0.0001292294,0.0001801535,0.0002275488,0.00004853247,0.001368671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005618887,"threshold_uncertainty_score":0.8167377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01115985325854921,"score_gpt":0.2315833178563555,"score_spread":0.2204234645978063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}