{"id":"W4224311696","doi":"10.1212/nxi.0000000000001173","title":"Programmed Cell Death Protein 1–Positive CD8 <sup>+</sup> T Cells in Multiple Sclerosis","year":2022,"lang":"en","type":"letter","venue":"Neurology Neuroimmunology & Neuroinflammation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Multiple sclerosis; Programmed cell death; CD8; Cytotoxic T cell; Cell; Cell biology; Chemistry; Biology; Immunology; Apoptosis; Biochemistry; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009684528,0.0006572743,0.001046646,0.0004982924,0.002194661,0.001462126,0.0009565208,0.02470783,0.002996033],"category_scores_gemma":[0.005809039,0.0004048823,0.0005794698,0.0003528598,0.001614997,0.001356006,0.0005426717,0.0108115,0.001878031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002743846,"about_ca_system_score_gemma":0.001128979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002310087,"about_ca_topic_score_gemma":0.002979129,"domain_scores_codex":[0.9993272,0.0002260591,0.00008952392,0.0000678691,0.0001636632,0.0001257189],"domain_scores_gemma":[0.9974582,0.001615722,0.0001550268,0.000110699,0.0003777587,0.0002825806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0006182341,0.0001258915,0.004450186,0.0002385372,0.00004890879,0.1149148,0.0002442284,0.000269061,0.002760026,0.005684034,0.8403491,0.03029688],"study_design_scores_gemma":[0.00148894,0.0007243637,0.01044137,0.0007799257,0.000223635,0.1845005,0.0008647658,0.006027865,0.00418817,0.04019855,0.7504405,0.0001213617],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01148606,0.005308462,0.0004431407,0.9445149,0.02186089,0.00003699711,0.00007930677,0.00008387143,0.01618638],"genre_scores_gemma":[0.1610887,0.005324551,0.001166179,0.664346,0.1407602,0.0001322265,0.0001124948,0.00006753267,0.02700202],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02470783,"threshold_uncertainty_score":0.01990807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03690327963531884,"score_gpt":0.249301075870539,"score_spread":0.2123977962352201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}