{"id":"W4224311696","doi":"10.1212/nxi.0000000000001173","title":"Programmed Cell Death Protein 1–Positive CD8 <sup>+</sup> T Cells in Multiple Sclerosis","year":2022,"lang":"en","type":"letter","venue":"Neurology Neuroimmunology & Neuroinflammation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Multiple sclerosis; Programmed cell death; CD8; Cytotoxic T cell; Cell; Cell biology; Chemistry; Biology; Immunology; Apoptosis; Biochemistry; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0007610878,0.001441042,0.002009552,0.002387163,0.0005064979,0.000123385,0.001262512,0.002499148,0.002992654],"category_scores_gemma":[0.0005398596,0.001625795,0.0006945285,0.001352292,0.0008095517,0.000288194,0.0009522858,0.01634634,0.0004682305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004099139,"about_ca_system_score_gemma":0.0006521968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003329291,"about_ca_topic_score_gemma":0.0000267633,"domain_scores_codex":[0.9868954,0.004549437,0.001826989,0.002886868,0.001360801,0.002480458],"domain_scores_gemma":[0.9945129,0.001633688,0.0009104672,0.002416265,0.0003248321,0.0002018289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007247108,0.0008806222,0.002825208,0.000554629,0.0002090906,0.02062513,0.0005650025,0.0008282551,0.9185552,0.00001440168,0.04164393,0.006051408],"study_design_scores_gemma":[0.01421396,0.01523989,0.02689005,0.0001717019,0.0004357438,0.002608115,0.00004403769,0.007107364,0.07376167,0.0001350982,0.8576356,0.001756763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.7293628,0.0001733229,0.000007368948,0.2602028,0.0006800925,0.007402305,0.0001137034,0.0004933611,0.001564228],"genre_scores_gemma":[0.3433284,0.001522971,0.000432001,0.6050429,0.00391109,0.008244956,0.006180553,0.002073212,0.02926384],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8447936,"threshold_uncertainty_score":0.9998339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03690327963531884,"score_gpt":0.249301075870539,"score_spread":0.2123977962352201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}