{"id":"W4224313263","doi":"10.3390/biology11050649","title":"Gene Editing of the Catfish Gonadotropin-Releasing Hormone Gene and Hormone Therapy to Control the Reproduction in Channel Catfish, Ictalurus punctatus","year":2022,"lang":"en","type":"article","venue":"Biology","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biology; Catfish; Ictalurus; Transcription activator-like effector nuclease; Mutant; Gene; Broodstock; Genetics; Molecular biology; Fishery; Genome; Aquaculture; Genome editing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000383622,0.0001500646,0.0001812293,0.00004949146,0.0002830016,0.000009357657,0.0002229407,0.00009531539,0.000003205854],"category_scores_gemma":[0.0001162958,0.00009953665,0.00006768199,0.0002240219,0.0001658597,0.000002520123,0.0002559154,0.0001699849,5.607713e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002890027,"about_ca_system_score_gemma":0.00005485153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002929785,"about_ca_topic_score_gemma":0.00002763058,"domain_scores_codex":[0.9985619,0.0002276553,0.0002746313,0.0005643381,0.0001007643,0.0002706769],"domain_scores_gemma":[0.9992101,0.00001163431,0.000164607,0.0004947771,0.00007990871,0.00003897084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003096502,0.00005460154,0.001554377,0.000002056062,0.00004023056,6.713939e-7,0.0002197245,0.0005216341,0.9909706,0.00002818623,0.0004906879,0.00580765],"study_design_scores_gemma":[0.002474673,0.003182789,0.4394239,0.000005020107,0.00004356715,0.0002630484,0.0008127637,0.0002097425,0.4868092,0.000329259,0.06601384,0.000432178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792361,0.01676463,0.0002335273,0.002563748,0.0006113501,0.0005167682,0.00003206148,0.000006878174,0.00003489204],"genre_scores_gemma":[0.9961714,0.002072742,0.00008829012,0.000448494,0.0009287664,0.0001032181,0.00004251786,0.00002073985,0.0001238223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5041613,"threshold_uncertainty_score":0.4058987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078220632995983,"score_gpt":0.2247222932370267,"score_spread":0.2139400869070668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}