{"id":"W4224316001","doi":"10.31083/ph.2022.11072","title":"Cytotoxic benzylidene hydrazides of terephthalic acid and related compounds","year":2022,"lang":"en","type":"article","venue":"Die Pharmazie","topic":"Chemical Synthesis and Reactions","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Terephthalic acid; Hydrazide; Phthalic acid; Chemistry; Isophthalic acid; Aryl; Cytotoxic T cell; Cytotoxicity; Stereochemistry; Organic chemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009289809,0.0002455087,0.0001935159,0.0001850056,0.00009660675,0.0001220664,0.0002133883,0.0001662525,0.001770156],"category_scores_gemma":[0.0001089524,0.00009711301,0.0001443421,0.0001670491,0.0001343216,0.0002010333,0.0001618728,0.0003454346,0.00040235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001380466,"about_ca_system_score_gemma":0.000136472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000166091,"about_ca_topic_score_gemma":0.0004682071,"domain_scores_codex":[0.9999461,0.000009687238,0.0000049716,0.000008752425,0.00001726515,0.00001318684],"domain_scores_gemma":[0.9999363,0.00001321305,0.000016362,0.00001319631,0.000009933234,0.00001099359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001292851,0.00004266608,0.000213878,0.0001995258,0.0000108355,0.0002727669,0.00002982162,0.0005297975,0.9879,0.0005990621,0.00009656596,0.009975751],"study_design_scores_gemma":[0.00001844927,0.0007049429,0.001499114,0.00001015205,0.00001791614,0.0004104025,0.000016685,0.0003255713,0.9917385,0.00008296437,0.005170827,0.00000447553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650687,0.01149307,0.01009181,0.0001854456,0.00005773392,0.0001639659,0.000774539,0.0001067253,0.01205795],"genre_scores_gemma":[0.9844115,0.007194532,0.003508948,0.00004835981,0.00002814657,0.00005757099,0.0004628457,0.00001396613,0.004274111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001770156,"threshold_uncertainty_score":0.005921781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526191320388883,"score_gpt":0.2473180063617217,"score_spread":0.2320560931578328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}