{"id":"W4224316001","doi":"10.31083/ph.2022.11072","title":"Cytotoxic benzylidene hydrazides of terephthalic acid and related compounds","year":2022,"lang":"en","type":"article","venue":"˜Die œPharmazie","topic":"Chemical Synthesis and Reactions","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Terephthalic acid; Hydrazide; Phthalic acid; Chemistry; Isophthalic acid; Aryl; Cytotoxic T cell; Cytotoxicity; Stereochemistry; Organic chemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000123276,0.0001565596,0.0002623122,0.00005126648,0.0002402758,0.00001857937,0.0002074464,0.00006987645,0.005593298],"category_scores_gemma":[0.00003224058,0.0001516126,0.0001250209,0.0001252541,0.0001149537,0.00006672283,0.0002637714,0.0003315333,0.00001541838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008999737,"about_ca_system_score_gemma":0.00002499255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007651369,"about_ca_topic_score_gemma":0.000003582727,"domain_scores_codex":[0.998873,0.00002555107,0.0003439019,0.0002834823,0.0002461477,0.000227942],"domain_scores_gemma":[0.9992936,0.0001286243,0.0001615742,0.0002776598,0.00002456689,0.000113943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003107666,0.0001863245,0.001657107,0.00006880462,0.0001060213,0.00002368018,0.0001749216,0.000009042154,0.9945242,0.00003491109,0.001458942,0.001724937],"study_design_scores_gemma":[0.0005773287,0.00001825167,0.0005101908,0.0000232162,0.00006032958,0.0001736897,0.0002586458,0.0001072991,0.9683475,0.0005278027,0.02920377,0.0001919398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9640063,0.001435676,8.352371e-7,0.0002833784,0.000105805,0.00005313808,0.00009660258,0.00008992285,0.03392832],"genre_scores_gemma":[0.9975456,0.0001460146,0.00003625953,0.00004921794,0.00006608642,0.00003928884,0.00005215623,0.0000279948,0.002037411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03353925,"threshold_uncertainty_score":0.9953157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526191320388883,"score_gpt":0.2473180063617217,"score_spread":0.2320560931578328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}