{"id":"W4224320539","doi":"10.1111/1462-2920.16029","title":"A functional <scp>Wood–Ljungdahl</scp> pathway devoid of a formate dehydrogenase in the gut acetogens <i>Blautia wexlerae</i> , <i>Blautia luti</i> and beyond","year":2022,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"Anaerobic Digestion and Biogas Production","field":"Engineering","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"H2020 European Research Council; Deutsche Forschungsgemeinschaft; European Commission; Emerald Foundation","keywords":"Acetogenesis; Formate dehydrogenase; Biology; Formate; Metagenomics; Carbon monoxide dehydrogenase; Biochemistry; Hydrogenase; Metabolic pathway; Enzyme; Bacteria; Gene; Methanogenesis; Genetics; Carbon monoxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003011858,0.0002155363,0.0002081568,0.0001068831,0.000181996,0.000009582401,0.0001827905,0.0000933015,0.0001989077],"category_scores_gemma":[0.000006999071,0.0001902284,0.00007712711,0.000154228,0.0002217235,0.00009357474,0.0001875222,0.0003309061,0.00004703654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001335785,"about_ca_system_score_gemma":0.00001373001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008670167,"about_ca_topic_score_gemma":0.00001642071,"domain_scores_codex":[0.9988077,0.000137412,0.000327511,0.0002961729,0.00009134848,0.0003398226],"domain_scores_gemma":[0.9995909,0.00005680997,0.00007691194,0.0002258398,0.000002695671,0.0000468533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000159932,0.0001560388,0.001661697,0.00001078642,0.00005120892,0.00001078929,0.001020927,0.003524021,0.9850958,0.0007214847,0.00715582,0.0005754109],"study_design_scores_gemma":[0.002610453,0.0005636099,0.01718532,0.00001261138,0.00008165189,0.002397917,0.006367987,0.0005366961,0.2605186,0.0003516344,0.7089563,0.0004172378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961658,0.001713357,0.0001013749,0.0002067798,0.0003898716,0.0003056362,0.0003922538,0.00005380646,0.0006711869],"genre_scores_gemma":[0.9982127,0.0002483481,0.0001254037,0.0006293578,0.00004530263,0.00006418483,0.0004573978,0.0000242597,0.0001930248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7245772,"threshold_uncertainty_score":0.7757288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004332658561998547,"score_gpt":0.1487024470701284,"score_spread":0.1443697885081298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}