{"id":"W4224322449","doi":"10.3390/vetsci9050203","title":"Characterization of Dosage Levels for In Ovo Administration of Innate Immune Stimulants for Prevention of Yolk Sac Infection in Chicks","year":2022,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Chicken Farmers of Saskatchewan; Agriculture and Agri-Food Canada; Canadian Poultry Research Council","keywords":"In ovo; Innate immune system; Biology; Immune system; TLR3; CpG site; Pharmacology; Immunity; Antibiotics; Yolk sac; Microbiology; Immunology; Toll-like receptor; Embryo; Biochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004754188,0.00005772306,0.0001816989,0.0002053519,0.00008399406,0.000003189356,0.00008890839,0.00004281625,0.00004277427],"category_scores_gemma":[0.00002705988,0.00005799858,0.00004984968,0.0002085813,0.0001532985,0.0002031592,0.00004402883,0.00004695806,1.394433e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001511812,"about_ca_system_score_gemma":0.00005835235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001310733,"about_ca_topic_score_gemma":0.0000240392,"domain_scores_codex":[0.9993072,0.00009207348,0.0003386103,0.0001284,0.00002813828,0.0001055676],"domain_scores_gemma":[0.9995499,0.00006329406,0.0003038322,0.00005389194,0.00002640027,0.000002640221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005347669,0.0001830908,0.003761146,0.0001060987,0.000007264939,2.030148e-7,0.0004250906,0.0001437452,0.992241,0.0001473864,0.000001295991,0.002448863],"study_design_scores_gemma":[0.000826115,0.004474583,0.2536117,0.00008929947,0.000005880016,0.00001231547,0.000257625,0.000142991,0.7401617,0.0002561747,0.00009172798,0.00006983464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981402,0.00004558657,0.0008794463,0.00002672949,0.000233441,0.0004268724,0.0002239427,0.000003959951,0.00001985721],"genre_scores_gemma":[0.9995328,0.00001978714,0.0001620189,0.000004141083,0.000004247127,0.00004871329,0.0001267423,0.000002956983,0.0000985551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2520793,"threshold_uncertainty_score":0.2365113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05616350468103228,"score_gpt":0.3146365544789659,"score_spread":0.2584730497979337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}