{"id":"W4224325453","doi":"10.3390/v14040657","title":"HBsAg Loss as a Treatment Endpoint for Chronic HBV Infection: HBV Cure","year":2022,"lang":"en","type":"review","venue":"Viruses","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Ottawa","funders":"","keywords":"HBsAg; Medicine; Virology; Hepatitis B virus; Chronic hepatitis; Clinical endpoint; Immunology; Internal medicine; Virus; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001931906,0.0007518434,0.002599122,0.0003179199,0.0003810446,0.00003738475,0.000142418,0.0002680474,0.003895697],"category_scores_gemma":[0.0003004874,0.0005624757,0.001157893,0.0003983144,0.0001155672,0.00008039775,0.0001816616,0.0003943906,0.0008470917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003061054,"about_ca_system_score_gemma":0.001671594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002475186,"about_ca_topic_score_gemma":0.001952815,"domain_scores_codex":[0.9974326,0.0001579979,0.0007471798,0.0007222889,0.0003818109,0.0005581518],"domain_scores_gemma":[0.9981782,0.0004956864,0.000366478,0.0007148677,0.00006614894,0.0001786463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004939116,0.0003818298,0.0002913146,0.01732507,0.001831418,0.0002228175,0.0001555863,5.197223e-7,8.326411e-7,0.0003372054,0.0120632,0.9673408],"study_design_scores_gemma":[0.00092344,0.002661883,0.00003468357,0.004180776,0.003742807,0.0002354761,0.000006577313,9.10371e-7,0.00002044211,0.00004055326,0.9877053,0.0004471042],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004245566,0.9915569,0.00001749874,0.000124526,0.001023713,0.003684133,0.0007272837,0.00025973,0.002563688],"genre_scores_gemma":[0.00001659013,0.98801,0.00008485412,0.0004172265,0.001789849,0.006070952,0.0003637214,0.0001736957,0.003073061],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9756421,"threshold_uncertainty_score":0.9999309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1887462104525544,"score_gpt":0.435281523147735,"score_spread":0.2465353126951806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}