{"id":"W4224325804","doi":"10.1261/rna.079159.122","title":"Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1","year":2022,"lang":"en","type":"article","venue":"RNA","topic":"Trace Elements in Health","field":"Nursing","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Phosphodiester bond; Biochemistry; Biology; Enzyme; Cofactor; RNA; Saccharomyces cerevisiae; Active site; Spliceosome; Yeast; Molecular biology; RNA splicing; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002930543,0.00009831443,0.0001977199,0.0000690001,0.0001858896,0.0000166591,0.0001250319,0.00002093732,0.0001183288],"category_scores_gemma":[0.00005957183,0.00008888695,0.00003774615,0.00008739025,0.00004631881,0.00008114607,0.0001181369,0.0002095444,0.000003779199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008449912,"about_ca_system_score_gemma":0.00002111337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006324841,"about_ca_topic_score_gemma":0.00005482955,"domain_scores_codex":[0.9988875,0.0001502059,0.0002645334,0.0001812639,0.0002874594,0.0002290824],"domain_scores_gemma":[0.9996069,0.00002624568,0.0001125136,0.0001752251,0.00002453676,0.00005457452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005340224,0.0003223105,0.004786325,0.0004622769,0.0001063079,0.00001208004,0.01058698,0.0002721612,0.9350943,0.001000732,0.0007048144,0.04611771],"study_design_scores_gemma":[0.005013844,0.002202232,0.08018661,0.0004602878,0.0003686883,0.0001578445,0.007467197,0.003732175,0.8716938,0.0006443292,0.02716872,0.0009042881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940115,0.003340676,0.00002922568,0.001017142,0.0009085888,0.0003072601,0.00002064153,0.00004317278,0.0003217523],"genre_scores_gemma":[0.998961,0.000008861652,0.0004137146,0.0003024274,0.00007988489,0.00002707314,0.000002700619,0.00002305931,0.0001812482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07540029,"threshold_uncertainty_score":0.3624705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05475476740658124,"score_gpt":0.2639916570286173,"score_spread":0.2092368896220361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}