{"id":"W4224433984","doi":"10.1128/mbio.01863-21","title":"The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter","year":2022,"lang":"en","type":"article","venue":"mBio","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Acinetobacter baumannii; Microbiology; Phenylacetic acid; Virulence; Biofilm; Biology; Operon; Transcriptome; Pathogen; Antibiotics; Gene silencing; Mutant; Chemistry; Gene; Bacteria; Biochemistry; Gene expression; Genetics; Pseudomonas aeruginosa","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008187902,0.0002092569,0.0001532397,0.0001428525,0.0001773645,0.0002579162,0.00009993155,0.0002259067,0.0005065116],"category_scores_gemma":[0.00008973631,0.00009208929,0.0001279675,0.0001212338,0.0001705294,0.0001595709,0.0001676863,0.0002791359,0.0001741904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002901503,"about_ca_system_score_gemma":0.00024726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009386636,"about_ca_topic_score_gemma":0.001013793,"domain_scores_codex":[0.9998906,0.00002347977,0.000007658222,0.00002269725,0.00002584746,0.00002975082],"domain_scores_gemma":[0.9999202,0.000008519892,0.00003154187,0.0000062183,0.00001393582,0.00001943631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008030575,0.00001312351,0.0003344909,0.00001243162,0.000001277209,0.00002495614,0.000008135825,0.00003068716,0.9988431,0.00003438631,0.00001823019,0.0005988278],"study_design_scores_gemma":[0.00001708758,0.0003022373,0.03593962,0.0000111057,0.00001441052,0.0002833223,0.0001570356,0.002222169,0.958249,0.0001763867,0.002615505,0.00001211013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938664,0.002541839,0.002018749,0.000243456,0.00002385743,0.00001229616,0.0002359285,0.00008220367,0.0009752693],"genre_scores_gemma":[0.9967608,0.0008908613,0.001065459,0.00006742252,0.00000564143,0.00001814862,0.0001760915,0.00001066809,0.001005061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009386636,"threshold_uncertainty_score":0.002105236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007360173676419614,"score_gpt":0.2304775988929168,"score_spread":0.2231174252164972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}