{"id":"W4224435322","doi":"10.1002/cbic.202200127","title":"2‐Aminopurine Fluorescence Spectroscopy for Probing a Glucose Binding Aptamer","year":2022,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Aptamer; Chemistry; Fluorescence; Fluorescence spectroscopy; Biosensor; Analyte; Binding site; Biophysics; Biochemistry; Chromatography; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001764348,0.0004547997,0.0001618313,0.0002374296,0.0001840378,0.0001552818,0.0002964397,0.0006270948,0.001034222],"category_scores_gemma":[0.0001979731,0.0001334266,0.0001145784,0.0001787992,0.0001678778,0.0001749355,0.0001741854,0.0004302947,0.0002572837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002308531,"about_ca_system_score_gemma":0.00009195977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004109608,"about_ca_topic_score_gemma":0.0003592349,"domain_scores_codex":[0.9997979,0.00006284501,0.000006667584,0.00004815076,0.00005383006,0.00003056979],"domain_scores_gemma":[0.9998744,0.00006224247,0.00002373601,0.000006891293,0.00001663439,0.00001607867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001595092,0.000006289094,0.00005907919,0.00001431538,0.000001320031,0.00002272397,0.000007522825,0.00007797041,0.9991589,0.00002472487,0.00001691732,0.0005943695],"study_design_scores_gemma":[0.000002476411,0.00007795711,0.0005957108,0.000001632627,0.000002109325,0.0000905251,0.0000074339,0.001468942,0.9973417,0.00001899113,0.0003887435,0.000003694208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9592076,0.001449253,0.03702717,0.0001556205,0.00004027251,0.00002793514,0.0001492816,0.0002444682,0.001698474],"genre_scores_gemma":[0.9772725,0.0005327374,0.0203105,0.0001116414,0.00001335679,0.00004477711,0.0001002009,0.00001851228,0.001595774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034222,"threshold_uncertainty_score":0.003459871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075805908443729,"score_gpt":0.2665976406023969,"score_spread":0.2558395815179597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}