{"id":"W4224438985","doi":"10.3390/membranes12050464","title":"Characterizing Extracellular Vesicles and Particles Derived from Skeletal Muscle Myoblasts and Myotubes and the Effect of Acute Contractile Activity","year":2022,"lang":"en","type":"article","venue":"Membranes","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Manitoba; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"University of Manitoba; Research Manitoba","keywords":"Myogenesis; C2C12; Myocyte; Skeletal muscle; Chemistry; Cell biology; Exosome; Extracellular; In vitro; Andrology; Biology; Molecular biology; Biochemistry; Microvesicles; Anatomy; Medicine; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003637268,0.000171877,0.0002530143,0.00002089533,0.0002423306,0.00004134756,0.000117806,0.00005388392,0.00001857022],"category_scores_gemma":[0.00007369748,0.0001340474,0.00006445351,0.00004018673,0.0004162078,0.00001612163,0.0003038407,0.0001166553,3.710713e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000432096,"about_ca_system_score_gemma":0.00001324481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006485671,"about_ca_topic_score_gemma":0.000008313463,"domain_scores_codex":[0.9987744,0.0004035355,0.0001625315,0.0003402067,0.0001362371,0.0001830559],"domain_scores_gemma":[0.9993234,0.0002084383,0.0001198666,0.0002541314,0.00001405611,0.00008006539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007255544,0.00003637115,0.003582516,0.00005820179,0.0001529243,0.00001535509,0.0002833204,0.000004460214,0.9757195,0.00001071661,0.000005405081,0.01940573],"study_design_scores_gemma":[0.002221924,0.0002518628,0.05690088,0.000009339461,0.0001974642,0.00002603015,0.000171747,0.0004895568,0.9386293,0.00006782362,0.0008793552,0.0001547217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875388,0.01171277,0.00003810976,0.0002183715,0.00005595786,0.0003084946,0.0001047631,0.00001248244,0.00001023205],"genre_scores_gemma":[0.9990956,0.0005846767,0.00006542812,0.00004886333,0.00006166173,0.00006414309,0.00003428497,0.00002207028,0.00002331549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05331836,"threshold_uncertainty_score":0.5466294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004526790739703301,"score_gpt":0.2129855837016965,"score_spread":0.2084587929619932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}