{"id":"W4224831002","doi":"10.3389/fimmu.2022.849515","title":"Combinatorial Herpes Simplex Vaccine Strategies: From Bedside to Bench and Back","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of Allergy and Infectious Diseases; National Eye Institute","keywords":"Bench to bedside; Virology; Medicine; Herpes simplex virus; Medical physics; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008353581,0.000667325,0.0009410098,0.0006156878,0.000265398,0.002178862,0.0007242534,0.0009002429,0.004153811],"category_scores_gemma":[0.00063156,0.0004509335,0.0005170105,0.0003843716,0.0006590456,0.002336637,0.001039589,0.002685038,0.001620895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006972104,"about_ca_system_score_gemma":0.0005152001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002163472,"about_ca_topic_score_gemma":0.0005408837,"domain_scores_codex":[0.9996489,0.00008909326,0.0000219026,0.00005585958,0.0001261869,0.00005804734],"domain_scores_gemma":[0.9998115,0.00006707449,0.00002185752,0.00001347787,0.00005226238,0.00003393806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006609934,0.0005858566,0.0004976465,0.008159362,0.0002362923,0.0006162575,0.0003531569,0.003425949,0.100196,0.05355053,0.03279202,0.7989259],"study_design_scores_gemma":[0.0002475137,0.003792207,0.0007700811,0.001956035,0.0002033636,0.001444369,0.0003071139,0.002360299,0.04871049,0.02766467,0.9124594,0.00008446952],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01934975,0.930052,0.020255,0.006387586,0.002771558,0.0001863857,0.0002435534,0.0003525031,0.0204017],"genre_scores_gemma":[0.08132275,0.8824501,0.01889518,0.005578652,0.001484801,0.0002437452,0.0004145866,0.0001049334,0.009505217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004153811,"threshold_uncertainty_score":0.01389593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0290243834846447,"score_gpt":0.320686816245717,"score_spread":0.2916624327610723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}