{"id":"W4224924691","doi":"10.1038/s41417-022-00471-4","title":"A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer","year":2022,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Vimentin; Cancer research; Oncogene; Biology; Epithelial–mesenchymal transition; Cell culture; Cancer; Cell growth; Molecular biology; Immunology; Cell cycle; Metastasis; Genetics; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002572017,0.0002796972,0.000532851,0.0001870897,0.0001850833,0.00002770964,0.0002045595,0.00005740048,0.01442728],"category_scores_gemma":[0.00001592881,0.0002611659,0.0001874735,0.0005782283,0.00009415604,0.00007342509,0.00009775875,0.0004699411,0.00001408106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009196431,"about_ca_system_score_gemma":0.0008063018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004672526,"about_ca_topic_score_gemma":0.0004752542,"domain_scores_codex":[0.9978107,0.0001340452,0.0003630288,0.0005784338,0.0005227934,0.0005909643],"domain_scores_gemma":[0.9989841,0.00005200368,0.000145021,0.0004462806,0.0001367612,0.0002358324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004504098,0.001032946,0.02000608,0.0001297817,0.0004923834,0.0007581933,0.002941153,0.0002123139,0.4360625,0.0001503743,0.012374,0.5213361],"study_design_scores_gemma":[0.02730166,0.001917746,0.1217036,0.0006358869,0.000484709,0.001043715,0.002131235,0.0003387544,0.4281757,0.0005238752,0.4138671,0.001876069],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.945262,0.04147926,0.00001681109,0.01009989,0.001355244,0.0006344626,0.0005177186,0.00005981102,0.0005748243],"genre_scores_gemma":[0.9811361,0.009777933,0.0001244298,0.005453268,0.000731474,0.001640023,0.00002998039,0.00007637397,0.001030367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5194601,"threshold_uncertainty_score":0.999984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03791895533200454,"score_gpt":0.3526620861537116,"score_spread":0.3147431308217071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}