{"id":"W4224925158","doi":"10.1073/pnas.2117633119","title":"The Wsp system of <i>Pseudomonas aeruginosa</i> links surface sensing and cell envelope stress","year":2022,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Cystic Fibrosis Foundation","keywords":"Periplasmic space; Pseudomonas aeruginosa; Cell envelope; Biofilm; Envelope (radar); Opportunistic pathogen; Cell biology; Bacteria; Cell; Cell membrane; Biology; Pathogen; Microbiology; Environmental stress; Biochemistry; Escherichia coli; Computer science; Genetics; Ecology; Gene; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298039,0.0005165762,0.0002023082,0.0002187329,0.0002534701,0.0003368664,0.0002379486,0.0002892077,0.001069687],"category_scores_gemma":[0.0001892531,0.0001316349,0.0002352273,0.0001773084,0.0002270126,0.0002372663,0.000333281,0.0006703953,0.0006580273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004541592,"about_ca_system_score_gemma":0.0002981343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001506126,"about_ca_topic_score_gemma":0.001357826,"domain_scores_codex":[0.9998273,0.00003041673,0.0000124186,0.00003001899,0.00006380101,0.00003616437],"domain_scores_gemma":[0.9999477,0.000007648339,0.00001288353,0.000007987058,0.000008981428,0.0000149355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001318319,0.000007012218,0.0001118844,0.00001601367,0.000001899407,0.00003132912,0.000006025411,0.00002606807,0.9989674,0.00008240132,0.00007152101,0.0006651987],"study_design_scores_gemma":[0.000004719429,0.00006980191,0.003563364,0.000003974726,0.000006930181,0.0002864393,0.00002646538,0.0008923808,0.9915992,0.00009540035,0.003444248,0.000007054336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731562,0.001156444,0.01815306,0.0007747618,0.00008121645,0.00009161486,0.0019159,0.0004459424,0.004224994],"genre_scores_gemma":[0.9770194,0.0009166127,0.0126876,0.0002707392,0.00002093979,0.00009189448,0.004031323,0.0000849799,0.004876566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001506126,"threshold_uncertainty_score":0.003578484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01428925790316969,"score_gpt":0.2380759125756311,"score_spread":0.2237866546724614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}