{"id":"W4224936038","doi":"10.1097/qai.0000000000002993","title":"Plasma Cell–Free Mitochondrial DNA as a Marker of Geriatric Syndromes in Older Adults With HIV","year":2022,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institute on Aging","keywords":"Biomarker; Human immunodeficiency virus (HIV); Senescence; Mitochondrial DNA; Cognition; Older people; Cognitive impairment","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008095171,0.0003329355,0.0003234917,0.0007653779,0.0002978647,0.0005641693,0.0002330118,0.0004155213,0.0009342805],"category_scores_gemma":[0.002548063,0.0001699241,0.0002002917,0.0006570347,0.0001774456,0.0003640247,0.0004050439,0.0003555798,0.000132431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001613661,"about_ca_system_score_gemma":0.0001765922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001585855,"about_ca_topic_score_gemma":0.002294987,"domain_scores_codex":[0.9997826,0.00006936507,0.00003772515,0.00004076732,0.00004324591,0.00002626875],"domain_scores_gemma":[0.9988678,0.0001768958,0.0005741747,0.00003726193,0.0001999537,0.0001440269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001125242,0.00002333374,0.9979966,0.00001745196,0.00002741045,0.00003737992,0.00006073827,0.00002203921,0.0002360248,0.000004524081,0.00003475931,0.00142708],"study_design_scores_gemma":[0.00001021817,0.0003070716,0.9985656,0.00002865367,0.00005382332,0.0003438793,0.0001900631,0.0001995546,0.0001424118,0.00002685115,0.0001284242,0.000003395499],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988152,0.0006630647,0.00008781143,0.00003103265,0.000005279434,0.00001248543,0.0001717075,0.000002811971,0.0002106107],"genre_scores_gemma":[0.9994962,0.0001457293,0.0001262948,0.00003038379,0.00000876325,0.000009330673,0.000114875,5.418315e-7,0.0000677708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001585855,"threshold_uncertainty_score":0.004281223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007957218929062863,"score_gpt":0.2463698812878493,"score_spread":0.2384126623587864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}