{"id":"W4224936420","doi":"10.3390/md20050292","title":"Natural Polyether Ionophores and Their Pharmacological Profile","year":2022,"lang":"en","type":"review","venue":"Marine Drugs","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lethbridge College","funders":"","keywords":"Antiprotozoal; Antiparasitic; Antifungal; Antimicrobial; Quantitative structure–activity relationship; Chemistry; Biological activity; Combinatorial chemistry; Mode of action; Biochemistry; Biology; Organic chemistry; Microbiology; Stereochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035317,0.0006720934,0.0008509763,0.001805877,0.0001610331,0.0005774157,0.0004664877,0.0005877317,0.002493531],"category_scores_gemma":[0.0002631176,0.0002333573,0.0003993347,0.001150554,0.0002789885,0.0007633941,0.0003742538,0.001054681,0.001238507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088441,"about_ca_system_score_gemma":0.0003648086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005105562,"about_ca_topic_score_gemma":0.0009371571,"domain_scores_codex":[0.9999108,0.00001002113,0.00001315655,0.00002041062,0.000035453,0.00001018204],"domain_scores_gemma":[0.9999136,0.00003764717,0.00001696305,0.000002981647,0.00002053696,0.000008403873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001392775,0.0001459385,0.0002233318,0.02662214,0.0001023211,0.0003823776,0.00006800252,0.001137503,0.03383856,0.003891498,0.005990589,0.9274585],"study_design_scores_gemma":[0.00002864222,0.0004676067,0.001946342,0.002414974,0.0002155491,0.002445546,0.00007199336,0.0003243867,0.01625411,0.001546429,0.9742413,0.00004309905],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001194479,0.9961816,0.0005237361,0.0001016541,0.0000986649,0.00001053223,0.00004970588,0.00001409758,0.001825476],"genre_scores_gemma":[0.004920475,0.992857,0.0005866039,0.000150651,0.00008177827,0.00001876564,0.00008795921,0.000002892654,0.001293838],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002493531,"threshold_uncertainty_score":0.00834167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02843397970761638,"score_gpt":0.3193627237684604,"score_spread":0.290928744060844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}