{"id":"W4224944657","doi":"10.7759/cureus.24513","title":"Acute Onset of a Life-Threatening Skin Toxicity Due to Osimertinib: Severe Psoriasis Versus Toxic Epidermal Necrolysis","year":2022,"lang":"en","type":"article","venue":"Cureus","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Toxic epidermal necrolysis; Medicine; Osimertinib; Dermatology; Psoriasis; Epidermal growth factor receptor; Lung cancer; Internal medicine; Cancer; Erlotinib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002040727,0.0003846118,0.0004892782,0.0002982264,0.000387111,0.0006100141,0.0001626913,0.0008888794,0.002627357],"category_scores_gemma":[0.0009570859,0.0001240205,0.0003030138,0.0002439259,0.0003114604,0.0005771753,0.0002987825,0.001072739,0.0006611569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003869829,"about_ca_system_score_gemma":0.0002105184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005030854,"about_ca_topic_score_gemma":0.0007419481,"domain_scores_codex":[0.9997585,0.00004815704,0.00003480617,0.00003251614,0.00003927548,0.00008669607],"domain_scores_gemma":[0.9995131,0.0001019107,0.0001814223,0.00002327036,0.00004886545,0.0001313861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00131274,0.0002447232,0.11434,0.0004922361,0.00008965174,0.774528,0.0003983601,0.0003231519,0.03337496,0.001759307,0.006224635,0.06691209],"study_design_scores_gemma":[0.00005546982,0.0004813751,0.04468266,0.00008776003,0.00005446328,0.9391119,0.0003574686,0.000499802,0.005864654,0.0005402218,0.008244134,0.00002014709],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9232793,0.02450971,0.00643173,0.004571526,0.0004470943,0.0001416058,0.0002629074,0.0003580131,0.03999817],"genre_scores_gemma":[0.9948139,0.001951682,0.0004859121,0.001090887,0.0002291728,0.000007405964,0.00006084156,0.00001503933,0.001345293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002627357,"threshold_uncertainty_score":0.008789361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02243875021385247,"score_gpt":0.3209426453791461,"score_spread":0.2985038951652936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}