{"id":"W4224983068","doi":"10.3390/biomedicines10050999","title":"Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS)/Drug-Induced Hypersensitivity Syndrome (DiHS)—Readdressing the DReSS","year":2022,"lang":"en","type":"review","venue":"Biomedicines","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Toronto","funders":"Canadian Dermatology Foundation","keywords":"Medicine; Immunology; Disease; Culprit; Eosinophilia; Drug; Pathogenesis; Human leukocyte antigen; Dermatology; Antigen; Pathology; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003714214,0.0006362877,0.0008827455,0.00220409,0.0002532177,0.0008031402,0.0004404559,0.0008021463,0.002873322],"category_scores_gemma":[0.0008724033,0.0001452865,0.0005175864,0.001581679,0.0003412212,0.001004949,0.0004127477,0.001128784,0.001155093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003386558,"about_ca_system_score_gemma":0.0007022454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006667398,"about_ca_topic_score_gemma":0.001306871,"domain_scores_codex":[0.9997399,0.00005111267,0.00005974041,0.00003978116,0.00008711075,0.00002230717],"domain_scores_gemma":[0.9995585,0.000203537,0.00009231558,0.00001218825,0.0001039895,0.00002933759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008684614,0.00007094331,0.0008469213,0.02345193,0.000131008,0.0007810107,0.00009780927,0.0001784255,0.001577567,0.002101875,0.03614994,0.9345257],"study_design_scores_gemma":[0.00002444354,0.0001490964,0.003956445,0.01141292,0.0002725612,0.01790681,0.0001727533,0.0001332984,0.0008509787,0.00174599,0.963339,0.00003572947],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002296533,0.9980573,0.00009896368,0.0002451034,0.0002496334,0.000004986151,0.00002154855,0.000007759496,0.001085043],"genre_scores_gemma":[0.001955532,0.9965828,0.0002048337,0.0003321511,0.0003225044,0.000005271992,0.00005288986,0.00000158558,0.0005425733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002873322,"threshold_uncertainty_score":0.009612262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05523930277821092,"score_gpt":0.3156599103964733,"score_spread":0.2604206076182624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}