{"id":"W4224983068","doi":"10.3390/biomedicines10050999","title":"Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS)/Drug-Induced Hypersensitivity Syndrome (DiHS)—Readdressing the DReSS","year":2022,"lang":"en","type":"review","venue":"Biomedicines","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Toronto","funders":"Canadian Dermatology Foundation","keywords":"Medicine; Immunology; Disease; Culprit; Eosinophilia; Drug; Pathogenesis; Human leukocyte antigen; Dermatology; Antigen; Pathology; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001057339,0.001142925,0.003201466,0.001082806,0.0008361223,0.0000968024,0.0003379466,0.0003781713,0.00001898548],"category_scores_gemma":[0.0002205534,0.0006755444,0.0004418651,0.001719817,0.0006144331,0.000269732,0.0002564606,0.001741933,0.00005510635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009282447,"about_ca_system_score_gemma":0.0008790244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007952612,"about_ca_topic_score_gemma":0.0000496297,"domain_scores_codex":[0.9948747,0.0006567463,0.001055982,0.001316932,0.00131172,0.0007839485],"domain_scores_gemma":[0.9957067,0.001117943,0.001038976,0.001502108,0.00017603,0.0004582086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002428597,0.0002479106,0.0000259496,0.01954291,0.001364343,0.002129554,0.0007900968,3.099149e-7,0.001071491,0.0000353037,0.0003642881,0.9744036],"study_design_scores_gemma":[0.001420125,0.0001503168,0.0009639796,0.05039736,0.009064875,0.07796232,0.003812883,0.00001658411,0.00001434413,0.000004130602,0.8552831,0.0009099983],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03298827,0.9545418,0.000003908778,0.0008259748,0.002831766,0.003952831,0.0001366257,0.0005095546,0.004209286],"genre_scores_gemma":[0.105115,0.8905576,0.00002423798,0.000159639,0.001170711,0.0004669786,0.0005091326,0.0002827438,0.001713889],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9734936,"threshold_uncertainty_score":0.9995696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05523930277821092,"score_gpt":0.3156599103964733,"score_spread":0.2604206076182624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}