{"id":"W4224990437","doi":"10.21203/rs.3.rs-1557481/v1","title":"Mapping the incidence of drug-induced liver injury worldwide: a systematic review and meta-analysis","year":2022,"lang":"en","type":"review","venue":"Research Square","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Meta-analysis; Drug; Liver injury; Incidence (geometry); Medicine; Internal medicine; Pharmacology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.02323289,0.0005888843,0.006235033,0.001460319,0.001154713,0.00007031605,0.00132679,0.0004937613,0.005038659],"category_scores_gemma":[0.002073181,0.0003706815,0.002652733,0.006414386,0.000336649,0.000154372,0.001000523,0.005626147,0.0001327398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003638689,"about_ca_system_score_gemma":0.0005143282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002930911,"about_ca_topic_score_gemma":0.0001207325,"domain_scores_codex":[0.9710334,0.02450988,0.001676216,0.0008069196,0.001225209,0.0007483477],"domain_scores_gemma":[0.9896775,0.007365722,0.001112935,0.001186502,0.0003969674,0.0002603241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008566263,0.000106059,0.000002089099,0.9113073,0.06601464,0.00003805392,0.0006049782,0.000001668537,0.000003833858,0.0001757732,0.0005827487,0.02115424],"study_design_scores_gemma":[0.00007668454,0.00007672765,0.000001800453,0.01779155,0.4679018,0.00004664877,0.0002804102,0.00004768026,0.00001900557,0.00006674172,0.5132909,0.0004000492],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000221103,0.9882051,0.000006329171,0.0004250114,0.0001220693,0.01025883,0.0003361633,0.00004792814,0.0005764643],"genre_scores_gemma":[0.001337889,0.9891457,0.00001285707,0.0004619744,0.00006279543,0.00713588,0.00005917079,0.00005358936,0.001730142],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8935158,"threshold_uncertainty_score":0.9998745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5637762485993909,"score_gpt":0.5544329368371926,"score_spread":0.00934331176219827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}